HMGCL Protein (AA 28-325) (His tag)

N° du produit ABIN667639

Détail du produit

Antigène: HMGCL (3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL))

Type de proteíne: Recombinant

Attributs du protein: AA 28-325

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette HMGCL protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: HMGCL, 28-325aa , Human, His tag, E.coli

Pureté: > 85 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 0.4M Urea

Stock: 4 °C

Détail du antigène

Antigène: HMGCL (3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL))

Autre désignation: HMGCL (HMGCL Produits)

Synonymes: Afu7g01720 Protein, AO090038000541 Protein, AW476067 Protein, HL Protein, zgc:56248 Protein, 3-hydroxymethyl-3-methylglutaryl-CoA lyase S homeolog Protein, 3-hydroxymethyl-3-methylglutaryl-CoA lyase Protein, 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase Protein, 3-hydroxy-3-methylglutaryl-Coenzyme A lyase Protein, hmgcl.S Protein, HMGCL Protein, AFUA_7G01720 Protein, NFIA_114450 Protein, ACLA_065820 Protein, AOR_1_910074 Protein, PMAA_004600 Protein, TSTA_103060 Protein, ARB_04874 Protein, TRV_06573 Protein, Hmgcl Protein, hmgcl Protein

Sujet: HMGCL, also known as hydroxymethylglutaryl-CoA lyase, is a mitochondrial matrix protein that belongs to the HMG-CoA lyase family. It exists as a homodimer and participates in leucine catabolism and ketogenesis, the hepatic synthesis of ketone bodies that, during fasting, provide a major source of energy for heart, brain and kidney. More specifically, it catalyzes the final step of these processes, the cleavage of 3-hydroxy-3-methylglutaryl-CoA to acetoacetic acid and acetyl-CoA. Recombinant human HMGCL protein, fused to His-tag at N-terminus, was expressed in E.coli. Synonyms: Hydroxymethylglutaryl-CoA lyase, 3-hydroxy-3-methylglutarate-CoA lyase, HL, HMG-CoA lyase, Hydroxymethylglutaryl-CoA lyase mitochondrial. NCBI no.: NP_000182

Poids moléculaire: 34.2 kDa (323aa)