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HPSE Produits

(Heparanase (HPSE))
Heparan sulfate proteoglycans are major components of the basement membrane and extracellular matrix. The protein encoded by this gene is an enzyme that cleaves heparan sulfate proteoglycans to permit cell movement through remodeling of the extracellular matrix. In addition, this cleavage can release bioactive molecules from the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].

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Catégories HPSE en vedette

HPSE Anticorps

High quality antibodies with extensive validation data.

HPSE Kits ELISA

Reliable ELISA kits for a wide range of species.

HPSE Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

HPSE recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (8)
N° du produit ABIN7438439
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (6)
N° du produit ABIN7437449
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7438010
Quantité 100 μL
Fiche technique Fiche technique

HPSE recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (6)
N° du produit ABIN6574194
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (5)
N° du produit ABIN6730979
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967351
Quantité 96 tests
Fiche technique Fiche technique

HPSE recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Synthetic
Validations
  • (3)
N° du produit ABIN1880256
Quantité 200 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1307050
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN3092979
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits HPSE

Jäkel, Bergmann, Toth, Assenov, van der Duin, Strobel, Hank, Klöppel, Dorrell, Grompe, Moss, Dor, Schirmacher, Plass, Popanda, Schmezer: "Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability." dans: Nature communications, Vol. 8, Issue 1, pp. 1323, (2018) (PubMed).

Zhao, Liu, Ten, Zhang, Yuan, Yu, An: "Plasma heparanase is associated with blood glucose levels but not urinary microalbumin excretion in type 2 diabetic nephropathy at the early stage." dans: Renal failure, Vol. 39, Issue 1, pp. 698-701, (2018) (PubMed).

Qin, Xu, Qi, Guo, Wang, Xu, Qiao, Gu, Niu: "Evaluation of the C-domain of heparanase during AGE-induced macrophage inflammatory response." dans: Experimental and therapeutic medicine, Vol. 14, Issue 2, pp. 1017-1022, (2017) (PubMed).

Liao, Wang, Hu, Liu, Shen, Zhang, Yu, Fan, Zhou: "PI-88 inhibits postoperative recurrence of hepatocellular carcinoma via disrupting the surge of heparanase after liver resection." dans: Tumour biology, Vol. 37, Issue 3, pp. 2987-98, (2016) (PubMed).

Masola, Zaza, Gambaro, Onisto, Bellin, Vischini, Khamaysi, Hassan, Hamoud, Nativ, N Heyman, Lupo, Vlodavsky, Abassi: "Heparanase: A Potential New Factor Involved in the Renal Epithelial Mesenchymal Transition (EMT) Induced by Ischemia/Reperfusion (I/R) Injury." dans: PLoS ONE, Vol. 11, Issue 7, pp. e0160074, (2016) (PubMed).

Zeng, Yao, Chen, Yan, Liu, Zhang, Feng, Wu, Liu: "Sphingosine-1-phosphate induced epithelial-mesenchymal transition of hepatocellular carcinoma via an MMP-7/ syndecan-1/TGF-β autocrine loop." dans: Oncotarget, Vol. 7, Issue 39, pp. 63324-63337, (2016) (PubMed).

Hu, Atik, Yu, Li, Zhang, Li, Cai, Yu, Chen, Li, Yuan: "Serum heparanase concentration and heparanase activity in patients with retinal vein occlusion." dans: Acta ophthalmologica, Vol. 95, Issue 1, pp. e62-e66, (2016) (PubMed).

Qing, Zhang, Chen, Li, Mao, Chen: "High glucose-induced intestinal epithelial barrier damage is aggravated by syndecan-1 destruction and heparanase overexpression." dans: Journal of cellular and molecular medicine, Vol. 19, Issue 6, pp. 1366-74, (2015) (PubMed).

Hu, Zhang, Jin, Zhu, Xu, Wu, Wang, Chen, Webster, Chen, Yu, Wang: "Heparanase released from mesenchymal stem cells activates integrin beta1/HIF-2alpha/Flk-1 signaling and promotes endothelial cell migration and angiogenesis." dans: Stem cells (Dayton, Ohio), Vol. 33, Issue 6, pp. 1850-62, (2015) (PubMed).

Chen, Zhang, Sun, Hu, Lu, Ma: "Unfractionated heparin attenuates intestinal injury in mouse model of sepsis by inhibiting heparanase." dans: International journal of clinical and experimental pathology, Vol. 8, Issue 5, pp. 4903-12, (2015) (PubMed).

Synonymes et noms alternatifs relatifs à HPSE

heparanase (HPSE), heparanase (hpse), heparanase (Hpse), Hep, hpa, HPA, Hpa, hpa1, HPA1, hpr1, HPR1, Hpr1, HPSE, hpse1, HPSE1, hse1, HSE1, im:7144134

Protein level used designations for HPSE

  • heparanase
  • endo-glucoronidase
  • heparanase-1
  • endoglycosidase heparanase
  • heparanase-like
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