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HRG Produits

(Histidine-Rich Glycoprotein (HRG))

Catégories

This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels. [provided by RefSeq, Jul 2008].

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Catégories HRG en vedette

HRG Anticorps

High quality antibodies with extensive validation data.

HRG Kits ELISA

Reliable ELISA kits for a wide range of species.

HRG Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

HRG recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (6)
N° du produit ABIN7427567
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7440872
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
N° du produit ABIN7434977
Quantité 100 μL
Fiche technique Fiche technique

HRG recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (6)
N° du produit ABIN6720587
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
N° du produit ABIN6956556
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967423
Quantité 96 tests
Fiche technique Fiche technique

HRG recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1307066
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3092974
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3137228
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits HRG

Mattii, Bianchi, Falleni, Frascarelli, Masini, Alì, Chiellini, Sabbatini: "Ultrastructural Localization of Histidine-rich Glycoprotein in Skeletal Muscle Fibers: Colocalization With AMP Deaminase." dans: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 68, Issue 2, pp. 139-148, (2020) (PubMed).

Aksornphusitaphong, Phupong: "Combination of serum histidine-rich glycoprotein and uterine artery Doppler to predict preeclampsia." dans: Hypertension research : official journal of the Japanese Society of Hypertension, Vol. 41, Issue 4, pp. 275-281, (2018) (PubMed).

Shemesh, Yu, Gaus, Seth, Swayze, Bennett, Geary, Henry, Wang: "Pharmacokinetic and Pharmacodynamic Investigations of ION-353382, a Model Antisense Oligonucleotide: Using Alpha-2-Macroglobulin and Murinoglobulin Double-Knockout Mice." dans: Nucleic acid therapeutics, Vol. 26, Issue 4, pp. 223-35, (2016) (PubMed).

Deuschle, Birkel, Hambruch, Hornberger, Kinzel, Perovi?-Ottstadt, Schulz, Hahn, Burnet, Kremoser: "The nuclear bile acid receptor FXR controls the liver derived tumor suppressor histidine-rich glycoprotein." dans: International journal of cancer. Journal international du cancer, Vol. 136, Issue 11, pp. 2693-704, (2015) (PubMed).

Glorieux, Mullen, Duranton, Filip, Gayrard, Husi, Schepers, Neirynck, Schanstra, Jankowski, Mischak, Argilés, Vanholder, Vlahou, Klein: "New insights in molecular mechanisms involved in chronic kidney disease using high-resolution plasma proteome analysis." dans: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, (2015) (PubMed).

Matboli, Eissa, Said: "Evaluation of histidine-rich glycoprotein tissue RNA and serum protein as novel markers for breast cancer." dans: Medical oncology (Northwood, London, England), Vol. 31, Issue 4, pp. 897, (2014) (PubMed).

Tugues, Roche, Noguer, Orlova, Bhoi, Padhan, Akerud, Honjo, Selvaraju, Mazzone, Tolmachev, Claesson-Welsh: "Histidine-rich glycoprotein uptake and turnover is mediated by mononuclear phagocytes." dans: PLoS ONE, Vol. 9, Issue 9, pp. e107483, (2014) (PubMed).

Gu, Duce, Valova, Wong, Bush, Petrou, Wiley: "P2X7 receptor-mediated scavenger activity of mononuclear phagocytes toward non-opsonized particles and apoptotic cells is inhibited by serum glycoproteins but remains active in cerebrospinal fluid." dans: The Journal of biological chemistry, Vol. 287, Issue 21, pp. 17318-30, (2012) (PubMed).

Bolin, Wikström, Wiberg-Itzel, Olsson, Ringvall, Sundström-Poromaa, Axelsson, Thilaganathan, Åkerud: "Prediction of preeclampsia by combining serum histidine-rich glycoprotein and uterine artery Doppler." dans: American journal of hypertension, Vol. 25, Issue 12, pp. 1305-10, (2012) (PubMed).

Wu, Xie, Liu, He, Benitez, Buckanovich, Lubman: "Identification and confirmation of differentially expressed fucosylated glycoproteins in the serum of ovarian cancer patients using a lectin array and LC-MS/MS." dans: Journal of proteome research, Vol. 11, Issue 9, pp. 4541-52, (2012) (PubMed).

Synonymes et noms alternatifs relatifs à HRG

histidine rich glycoprotein (HRG), histidine-rich glycoprotein (LOAG_12427), histidine-rich glycoprotein (LOC100597044), histidine-rich glycoprotein (Hrg), AI265597, AW413091, D16jh2, D18020, Hprg, HPRG, HRG1, Hrgp, HRGP, THPH11

Protein level used designations for HRG

  • histidine-rich glycoprotein
  • histidine-proline-rich glycoprotein
  • histidine-rich glycoprotein 1
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