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HRK Produits

(Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))

Catégories

This gene encodes a member of the BCL-2 protein family. Members of this family are involved in activating or inhibiting apoptosis. The encoded protein localizes to intracellular membranes. This protein promotes apoptosis by interacting with the apoptotic inhibitors BCL-2 and BCL-X(L) via its BH3 domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012].

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Catégories HRK en vedette

HRK Anticorps

High quality antibodies with extensive validation data.

HRK Kits ELISA

Reliable ELISA kits for a wide range of species.

HRK recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (1)
  • (2)
N° du produit ABIN543406
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (3)
  • (1)
N° du produit ABIN2474088
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (2)
N° du produit ABIN388104
Quantité 400 μL
Fiche technique Fiche technique

HRK recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN1120325
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1120326
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method
Validations
N° du produit ABIN1120327
Quantité 96 tests
Fiche technique Fiche technique

HRK recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3120786
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3109329
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits HRK

Lucas, Milani, Butterworth, Carmell, Scott, Clark, Cohen, Varadarajan: "High CIP2A levels correlate with an antiapoptotic phenotype that can be overcome by targeting BCL-XL in chronic myeloid leukemia." dans: Leukemia, Vol. 30, Issue 6, pp. 1273-81, (2016) (PubMed).

Conery, Centore, Spillane, Follmer, Bommi-Reddy, Hatton, Bryant, Greninger, Amzallag, Benes, Mertz, Sims: "Preclinical Anticancer Efficacy of BET Bromodomain Inhibitors Is Determined by the Apoptotic Response." dans: Cancer research, Vol. 76, Issue 6, pp. 1313-9, (2016) (PubMed).

Nakamura, Ishida, Shimada, Nakase, Sakaki, Konishi: "Frequent HRK inactivation associated with low apoptotic index in secondary glioblastomas." dans: Acta neuropathologica, Vol. 110, Issue 4, pp. 402-10, (2005) (PubMed).

Sunayama, Ando, Itoh, Tomiyama, Sakurada, Sugiyama, Kang, Tashiro, Gotoh, Kuchino, Kitanaka: "Physical and functional interaction between BH3-only protein Hrk and mitochondrial pore-forming protein p32." dans: Cell death and differentiation, Vol. 11, Issue 7, pp. 771-81, (2004) (PubMed).

Wakabayashi, Kosaka, Hommura: "Up-regulation of Hrk, a regulator of cell death, in retinal ganglion cells of axotomized rat retina." dans: Neuroscience letters, Vol. 318, Issue 2, pp. 77-80, (2002) (PubMed).

Sanz, Mellstrom, Link, Naranjo, Fernandez-Luna: "Interleukin 3-dependent activation of DREAM is involved in transcriptional silencing of the apoptotic Hrk gene in hematopoietic progenitor cells." dans: The EMBO journal, Vol. 20, Issue 9, pp. 2286-92, (2001) (PubMed).

Lockshin, Osborne, Zakeri: "Cell death in the third millennium." dans: Cell death and differentiation, Vol. 7, Issue 1, pp. 2-7, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à HRK

harakiri, BCL2 interacting protein (HRK), harakiri, BCL2 interacting protein (contains only BH3 domain) (Hrk), harakiri, BCL2 interacting protein (Hrk), AI838259, Bid3, DP5, Dp5, HARAKIRI, harakiri

Protein level used designations for HRK

  • BCL2-interacting protein
  • BH3-interacting domain-containing protein 3
  • activator of apoptosis Hrk
  • activator of apoptosis harakiri
  • death protein 5
  • neuronal death protein DP5
  • BH3 interacting (with BCL2 family) domain, apoptosis agonist
  • BH3 interacting domain 3
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