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HYOU1 Produits

(Hypoxia Up Regulated 1 (HYOU1))

Catégories

The protein encoded by this gene belongs to the heat shock protein 70 family. This gene uses alternative transcription start sites. A cis-acting segment found in the 5' UTR is involved in stress-dependent induction, resulting in the accumulation of this protein in the endoplasmic reticulum (ER) under hypoxic conditions. The protein encoded by this gene is thought to play an important role in protein folding and secretion in the ER. Since suppression of the protein is associated with accelerated apoptosis, it is also suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. This protein has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness. This gene also has an alternative translation initiation site, resulting in a protein that lacks the N-terminal signal peptide. This signal peptide-lacking protein, which is only 3 amino acids shorter than the mature protein in the ER, is thought to have a housekeeping function in the cytosol. In rat, this protein localizes to both the ER by a carboxy-terminal peptide sequence and to mitochondria by an amino-terminal targeting signal. [provided by RefSeq, Oct 2008].

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Catégories HYOU1 en vedette

HYOU1 Anticorps

High quality antibodies with extensive validation data.

HYOU1 Kits ELISA

Reliable ELISA kits for a wide range of species.

HYOU1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

HYOU1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IF, IHC (p), ICC
Validations
  • (8)
N° du produit ABIN2855339
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (3)
  • (4)
N° du produit ABIN564589
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Rat
Application WB, IHC, ELISA, IHC (p)
Validations
  • (4)
N° du produit ABIN396969
Quantité 50 μg
Fiche technique Fiche technique

HYOU1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967510
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6960602
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6951267
Quantité 96 tests
Fiche technique Fiche technique

HYOU1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1307316
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1307312
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1307314
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits HYOU1

Fauzia, Barbhuyan, Shrivastava, Kumar, Garg, Khan, Robertson, Raza: "Chick Embryo: A Preclinical Model for Understanding Ischemia-Reperfusion Mechanism." dans: Frontiers in pharmacology, Vol. 9, pp. 1034, (2018) (PubMed).

Du, Rong, Hui, Peng, Jin, Li, Wang, Li: "Expression and function of HSP110 family in mouse testis after vasectomy." dans: Asian journal of andrology, Vol. 19, Issue 3, pp. 355-361, (2016) (PubMed).

Ruan, Huang, Jin, Chen, Li, Gong: "Tetrandrine attenuated cerebral ischemia/reperfusion injury and induced differential proteomic changes in a MCAO mice model using 2-D DIGE." dans: Neurochemical research, Vol. 38, Issue 9, pp. 1871-9, (2013) (PubMed).

Yoshida, Yamashita, Nagano, Imai, Nabeshi, Yoshikawa, Yoshioka, Abe, Kamada, Tsutsumi, Tsunoda: "Limited expression of reticulocalbin-1 in lymphatic endothelial cells in lung tumor but not in normal lung." dans: Biochemical and biophysical research communications, Vol. 405, Issue 4, pp. 610-4, (2011) (PubMed).

Liu, Li, Bai, Zhang, Tang, Lei, Chen, Liang, Zhao, Wei, Huang: "Mechanism of cancer cell adaptation to metabolic stress: proteomics identification of a novel thyroid hormone-mediated gastric carcinogenic signaling pathway." dans: Molecular & cellular proteomics : MCP, Vol. 8, Issue 1, pp. 70-85, (2009) (PubMed).

Lindenmeyer, Rastaldi, Ikehata, Neusser, Kretzler, Cohen, Schlöndorff: "Proteinuria and hyperglycemia induce endoplasmic reticulum stress." dans: Journal of the American Society of Nephrology : JASN, Vol. 19, Issue 11, pp. 2225-36, (2008) (PubMed).

Synonymes et noms alternatifs relatifs à HYOU1

hypoxia up-regulated 1 (HYOU1), hypoxia up-regulated 1 (Hyou1), hypoxia up-regulated 1 (hyou1), hypoxia up-regulated protein 1 (LOC100380749), hypoxia up-regulated 1 S homeolog (hyou1.S), AI415631, Cab140, CBP-140, GRP-170, Grp170, GRP170, HSP12A, HYOU1, id:ibd5056, ORP-150, ORP150, Orp150, orp150, wu:fd14c05, zgc:56019

Protein level used designations for HYOU1

  • 150 kDa oxygen-regulated protein
  • 170 kDa glucose-regulated protein
  • glucose-regulated protein 170
  • hypoxia up-regulated protein 1
  • oxygen regulated protein (150kD)
  • 140 kDa Ca(2+)-binding protein
  • 150-kDa oxygen regulated protein
  • 170 kDa glucose regulated protein GRP170
  • GRP-170
  • calcium binding protein 140
  • calcium binding protein, 140 kDa
  • ORP-150
  • hypoxia up-regulated 1
  • Hypoxia up-regulated protein 1
  • hypoxia up-regulated protein 1-like
  • glucose regulated protein, 170 kDa
  • oxygen regulated protein, 150 kDa
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