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IL-1 beta Protéines

(Interleukin 1, beta (IL1B))
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008].

87 Résultats

IL1B Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
N° du produit ABIN7274882
 
IL1B Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE, > 95 % as determined by HPLC
N° du produit ABIN7274883
 
IL1B Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Pubmed 1 reference
N° du produit ABIN1307738
 
IL1B Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
N° du produit ABIN6964158
 
IL1B Origine: Poulet Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
N° du produit ABIN7123528
 
IL1B Origine: Chévre Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
N° du produit ABIN7123530
 
IL1B Origine: Chien Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
N° du produit ABIN7123529
 
IL1B Origine: Porc Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
N° du produit ABIN7123535
 
IL1B Origine: Cheval Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
N° du produit ABIN7123532
 
IL1B Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
N° du produit ABIN1307742
 
IL1B Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 97 % as determined by SDS-PAGE Active
N° du produit ABIN7320465
 
IL1B Origine: Rat Hôte: Escherichia coli (E. coli) Recombinant > 98 % as determined by SDS-PAGE Active
N° du produit ABIN7321252
 
IL1B Origine: Humain Hôte: Escherichia coli (E. coli) > 95 % AcA, CC Active
N° du produit ABIN6239756
 
IL1B Origine: Mouton Hôte: Levure Recombinant > 90 % ELISA
N° du produit ABIN7479109
 
IL1B Origine: Humain Hôte: HEK-293 Cells > 95 % AcA, CC Active
N° du produit ABIN6239741
 
IL1B Origine: Lapin Hôte: Escherichia coli (E. coli) Recombinant > 80 % as determined by reducing SDS-PAGE.
N° du produit ABIN7505461
 
IL1B Origine: Porc Hôte: Escherichia coli (E. coli) Recombinant > 98 % CC Active
N° du produit ABIN7669000
 
IL1B Origine: Humain Hôte: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
N° du produit ABIN2018033
 
IL1B Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant >95 % (SDS-PAGE) SDS Active
N° du produit ABIN1343986
 
IL1B Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant >95 % (SDS-PAGE) SDS
N° du produit ABIN1343988
 
  • Type Protein
    • Protein
  • Application
    • SDS-PAGE (SDS)
    • ELISA
    • Western Blotting (WB)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Activity Assay (AcA)
    • Cell Culture (CC)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Functional Studies (Func)
    • Immunoprecipitation (IP)
    • Antibody Production (AbP)
    • Flow Cytometry (FACS)
    • Standard (STD)
  • Réactivité
    • Human
    • Mouse
    • Rat
    • Pig
    • Rabbit
    • Chicken
    • Cow
    • Dog
    • Horse
    • Guinea Pig
    • Rhesus Monkey
    • Sheep
    • Cynomolgus
    • Goat
    • Beluga
    • Cat
    • Llama
    • Macaca nemestrina
    • Monkey
    • Red Deer
    • White-eyelid mangabey (Cercocebus)
    • Zebrafish (Danio rerio)
  • Cité dans publications
  • Images disponible
  • Sans conservateur uniquement
  • Carrier free only
  • Hote
    • Escherichia coli (E. coli)
    • Yeast
    • HEK-293 Cells
    • CHO Cells
    • Wheat germ
  • Epitope
    • AA 117-269
    • AA 114-266
    • AA 117-268
    • AA 118-269
    • AA 115-266
    • AA 115-267
    • AA 1-266
    • AA 116-268
    • AA 1-267
    • AA 1-269
    • AA 1-273
    • AA 103-260
    • AA 106-267
    • AA 109-251
    • AA 110-263
    • AA 114-265
    • AA 116-267
    • AA 118-268
    • AA 119-268
    • AA 13-242
    • AA 170-269
    • AA 63-247
    • AA 95-262
    • full length
    • partial
  • Conjugué
    • His tag
    • Inconjugué
    • GST tag
    • Fc Tag
    • His-Avi Tag,Biotin
    • His tag,GST tag
    • His-Avi Tag
    • Myc-DYKDDDDK Tag
  • Type Proteine
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Activité biologique
    • Biologically Active
    • Biologically Inactive
  • Grade
    • Animal-Free
    • MALS verified
  • Supplier
    • antibodies-online
    • CUSABIO
    • Rockland
    • Abbexa
    • ACROBiosystems
    • Cloud-Clone
    • ITSI-Biosciences
    • Signalway
    • BioLegend
    • OriGene

Dernières publications pour nos IL-1 beta Protéines

Shao, Fang, Dang, Xue, Zhang, Li, Qiao, Cao, Zhuang, Shen, Zhang, Qiao, Li, Gudjonsson, Wang: "Neutrophil Extracellular Traps Promote Inflammatory Responses in Psoriasis via Activating Epidermal TLR4/IL-36R Crosstalk." dans: Frontiers in immunology, Vol. 10, pp. 746, (2020) (PubMed).

Luo, Huang, He, Liu, Chen, Liu, Mi, Li, Sun, Li, Xiang, Su: "Inflammatory Human Umbilical Cord-Derived Mesenchymal Stem Cells Promote Stem Cell-Like Characteristics of Cancer Cells in an IL-1β-Dependent Manner." dans: BioMed research international, Vol. 2018, pp. 7096707, (2018) (PubMed).

Hollborn, Vogler, Reichenbach, Wiedemann, Bringmann, Kohen: "Regulation of the hyperosmotic induction of aquaporin 5 and VEGF in retinal pigment epithelial cells: involvement of NFAT5." dans: Molecular vision, Vol. 21, pp. 360-77, (2015) (PubMed).

Ubertini, Norelli, DArcangelo, Gurtner, Cesareo, Baldari, Gentileschi, Piaggio, Nisticò, Soddu, Facchiano, Bossi: "Mutant p53 gains new function in promoting inflammatory signals by repression of the secreted interleukin-1 receptor antagonist." dans: Oncogene, Vol. 34, Issue 19, pp. 2493-504, (2015) (PubMed).

von Burg, Chappaz, Baerenwaldt, Horvath, Bose Dasgupta, Ashok, Pieters, Tacchini-Cottier, Rolink, Acha-Orbea, Finke: "Activated group 3 innate lymphoid cells promote T-cell-mediated immune responses." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 35, pp. 12835-40, (2014) (PubMed).

Nikolakopoulou, Dutta, Chen, Miller, Trapp: "Activated microglia enhance neurogenesis via trypsinogen secretion." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 21, pp. 8714-9, (2013) (PubMed).

Kahlenberg, Thacker, Berthier, Cohen, Kretzler, Kaplan: "Inflammasome activation of IL-18 results in endothelial progenitor cell dysfunction in systemic lupus erythematosus." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 11, pp. 6143-56, (2011) (PubMed).

Zhang, Bennett, Verkman: "Ex vivo spinal cord slice model of neuromyelitis optica reveals novel immunopathogenic mechanisms." dans: Annals of neurology, Vol. 70, Issue 6, pp. 943-54, (2011) (PubMed).

Tiwari, Wang, Brochetta, Ke, Vita, Qi, Rivera, Soranzo, Zabucchi, Hong, Blank: "VAMP-8 segregates mast cell-preformed mediator exocytosis from cytokine trafficking pathways." dans: Blood, Vol. 111, Issue 7, pp. 3665-74, (2008) (PubMed).

Yang, Poon, Luo, Cheung, Ho, Lo, Fan: "Up-regulation of vascular endothelial growth factor (VEGF) in small-for-size liver grafts enhances macrophage activities through VEGF receptor 2-dependent pathway." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 4, pp. 2507-15, (2004) (PubMed).

Pseudonymes pour IL-1 beta Protéines

interleukin 1 beta (IL1B) Protéines
interleukin 1, beta (IL1B) Protéines
interleukin 1, beta (il1b) Protéines
interleukin 1 beta (Il1b) Protéines
IL-1 Protéines
IL-1 beta Protéines
IL-1B Protéines
Il-1b Protéines
IL-1b Protéines
IL-1BETA Protéines
IL-1beta Protéines
il1-b Protéines
IL1-BETA Protéines
IL1B Protéines
IL1beta Protéines
IL1F2 Protéines
zgc:111873 Protéines
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