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IL1RN Produits

(Interleukin 1 Receptor Antagonist (IL1RN))

Catégories

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

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Catégories IL1RN en vedette

IL1RN Anticorps

High quality antibodies with extensive validation data.

IL1RN Kits ELISA

Reliable ELISA kits for a wide range of species.

IL1RN Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

IL1RN recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ICC, IF, IHC (p)
Validations
  • (1)
  • (6)
N° du produit ABIN2856394
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7431371
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7425773
Quantité 100 μL
Fiche technique Fiche technique

IL1RN recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
N° du produit ABIN6956957
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Dog
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
N° du produit ABIN6956955
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6956958
Quantité 96 tests
Fiche technique Fiche technique

IL1RN recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1307765
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN988019
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123525
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits IL1RN

Pfeifer, Thurner, Kessel, Fadle, Kheiroddin, Regitz, Hoffmann, Kos, Preuss, Fischer, Roemer, Lohse, Heyne, Detemple, Fedlmeier, Juenger, Sauer, Meyer, Rohrer, Wittkowski, Becker, Masjosthusmann, Bals et al.: "Autoantibodies against interleukin-1 receptor antagonist in multisystem inflammatory syndrome in children: a multicentre, retrospective, cohort study. ..." dans: The Lancet. Rheumatology, Vol. 4, Issue 5, pp. e329-e337, (2022) (PubMed).

Wang, Zhen, Fan, Qin, Han, Zhou, Wang, An: "Axl Deficiency Promotes the Neuroinvasion of Japanese Encephalitis Virus by Enhancing IL-1α Production from Pyroptotic Macrophages." dans: Journal of virology, Vol. 94, Issue 17, (2020) (PubMed).

Kurowski, Jurczyk, Olszewska-Ziąber, Jarzębska, Krysztofiak, Kowalski: "A similar pro/anti-inflammatory cytokine balance is present in the airways of competitive athletes and non-exercising asthmatics." dans: Advances in medical sciences, Vol. 63, Issue 1, pp. 79-86, (2018) (PubMed).

Al-Nashmi, Taha, Alsharoqi, Bakhiet: "Interleukin 1 receptor antagonist and 2'-5'-oligoadenylate synthetase-like molecules as novel biomarkers for multiple sclerosis patients in Bahrain." dans: Multiple sclerosis and related disorders, Vol. 18, pp. 1-7, (2018) (PubMed).

Hull, Gibson, McNamara, Deutsch, Fligner, Frevert, Ramsey, Sanda: "Islet Interleukin-1β Immunoreactivity Is an Early Feature of Cystic Fibrosis That May Contribute to β-Cell Failure." dans: Diabetes Care, Vol. 41, Issue 4, pp. 823-830, (2018) (PubMed).

Esfahani, Saidijam, Najafi, Goodarzi, Movahedian: "The effect of salusin-β on expression of pro- and anti-inflammatory cytokines in human umbilical vein endothelial cells (HUVECs)." dans: ARYA atherosclerosis, Vol. 14, Issue 1, pp. 1-10, (2018) (PubMed).

Luo, Huang, He, Liu, Chen, Liu, Mi, Li, Sun, Li, Xiang, Su: "Inflammatory Human Umbilical Cord-Derived Mesenchymal Stem Cells Promote Stem Cell-Like Characteristics of Cancer Cells in an IL-1β-Dependent Manner." dans: BioMed research international, Vol. 2018, pp. 7096707, (2018) (PubMed).

Kurowski, Jurczyk, Moskwa, Jarzębska, Krysztofiak, Kowalski: "Winter ambient training conditions are associated with increased bronchial hyperreactivity and with shifts in serum innate immunity proteins in young competitive speed skaters." dans: Archives of medical science : AMS, Vol. 14, Issue 1, pp. 60-68, (2018) (PubMed).

Ogawa, Osada, Hasegawa, Ohno, Yanuma, Sasaki, Shimoda, Shirai, Kondo, Ohmori: "Effect of interleukin-1β on occludin mRNA expression in the duodenal and colonic mucosa of dogs with inflammatory bowel disease." dans: Journal of veterinary internal medicine, Vol. 32, Issue 3, pp. 1019-1025, (2018) (PubMed).

Køllgaard, Enevold, Bendtzen, Hansen, Givskov, Holmstrup, Nielsen: "Cholesterol crystals enhance TLR2- and TLR4-mediated pro-inflammatory cytokine responses of monocytes to the proatherogenic oral bacterium Porphyromonas gingivalis." dans: PLoS ONE, Vol. 12, Issue 2, pp. e0172773, (2017) (PubMed).

Synonymes et noms alternatifs relatifs à IL1RN

interleukin 1 receptor antagonist (IL1RN), interleukin 1 receptor antagonist (Il1rn), interleukin 1 receptor antagonist-like (IL1RNL), DIRA, F630041P17Rik, ICIL-1RA, IL-1ra, IL-1RA, IL-1ra3, IL-1RN, IL1F3, IL1RA, IL1RN, IRAP, IRAP1, MVCD4

Protein level used designations for IL1RN

  • IL1 inhibitor
  • IL1RN (IL1F3)
  • interleukin-1 receptor antagonist protein
  • intracellular IL-1 receptor antagonist type II
  • intracellular interleukin-1 receptor antagonist (icIL-1ra)
  • type II interleukin-1 receptor antagonist
  • IL-1RN
  • IL-1ra
  • IRAP
  • interleukin 1 receptor antagonist
  • interleukin-1 receptor antagonist secretory form
  • secretory interleukin-1 receptor antagonist
  • IL-1 receptor antagonist
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