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IL27 Receptor alpha Produits

(Interleukin 27 Receptor, alpha (IL27RA))
In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein. [provided by RefSeq, Jul 2008].

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Catégories IL27 Receptor alpha en vedette

IL27 Receptor alpha Anticorps

High quality antibodies with extensive validation data.

IL27 Receptor alpha Kits ELISA

Reliable ELISA kits for a wide range of species.

IL27 Receptor alpha Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

IL27 Receptor alpha recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro)
Validations
  • (1)
  • (4)
N° du produit ABIN749498
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
N° du produit ABIN7156877
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (2)
N° du produit ABIN7444133
Quantité 100 μL
Fiche technique Fiche technique

IL27 Receptor alpha recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN4883399
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
N° du produit ABIN6384792
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN842000
Quantité 96 tests
Fiche technique Fiche technique

IL27 Receptor alpha recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7275016
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
N° du produit ABIN7275033
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1307804
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits IL27 Receptor alpha

Xu, Yi, Wang, Hu, Han, Xue, Zhang, Luan: "IL-27 regulates the adherence, proliferation, and migration of MSCs and enhances their regulatory effects on Th1 and Th2 subset generations." dans: Immunologic research, Vol. 65, Issue 4, pp. 903-912, (2017) (PubMed).

Vijayan, Mohd Redzwan, Avery, Wirasinha, Brink, Walters, Adelstein, Kobayashi, Gray, Elliott, Wong, King, Vinuesa, Ghilardi, Ma, Tangye, Batten: "IL-27 Directly Enhances Germinal Center B Cell Activity and Potentiates Lupus in Sanroque Mice." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 8, pp. 3008-3017, (2016) (PubMed).

Di Carlo, Sorrentino, Zorzoli, Di Meo, Tupone, Ognio, Mincione, Airoldi: "The antitumor potential of Interleukin-27 in prostate cancer." dans: Oncotarget, Vol. 5, Issue 21, pp. 10332-41, (2015) (PubMed).

Morandi, Di Carlo, Ferrone, Petretto, Pistoia, Airoldi: "IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 6, pp. 2634-42, (2014) (PubMed).

Mascanfroni, Yeste, Vieira, Burns, Patel, Sloma, Wu, Mayo, Ben-Hamo, Efroni, Kuchroo, Robson, Quintana: "IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39." dans: Nature immunology, Vol. 14, Issue 10, pp. 1054-63, (2013) (PubMed).

Kachroo, Lee, Zhang, Baratelli, Lee, Srivastava, Wang, Walser, Krysan, Sharma, Dubinett, Lee: "IL-27 inhibits epithelial-mesenchymal transition and angiogenic factor production in a STAT1-dominant pathway in human non-small cell lung cancer." dans: Journal of experimental & clinical cancer research : CR, Vol. 32, pp. 97, (2013) (PubMed).

Tzeng, Tsay, Chang, Hsu, Lai, Huang, Shiao: "Caspase 3 involves in neuroplasticity, microglial activation and neurogenesis in the mice hippocampus after intracerebral injection of kainic acid." dans: Journal of biomedical science, Vol. 20, pp. 90, (2013) (PubMed).

Guzzo, Hopman, Che Mat, Wobeser, Gee: "IL-27-induced gene expression is downregulated in HIV-infected subjects." dans: PLoS ONE, Vol. 7, Issue 9, pp. e45706, (2012) (PubMed).

Cocco, Di Carlo, Zupo, Canale, Zorzoli, Ribatti, Morandi, Ognio, Airoldi: "Complementary IL-23 and IL-27 anti-tumor activities cause strong inhibition of human follicular and diffuse large B-cell lymphoma growth in vivo." dans: Leukemia, Vol. 26, Issue 6, pp. 1365-74, (2012) (PubMed).

Pradhan, Lambert, Reuther: "Transformation of hematopoietic cells and activation of JAK2-V617F by IL-27R, a component of a heterodimeric type I cytokine receptor." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 47, pp. 18502-7, (2007) (PubMed).

Synonymes et noms alternatifs relatifs à IL27 Receptor alpha

interleukin 27 receptor subunit alpha (IL27RA), interleukin-27 receptor subunit alpha (LOC484907), interleukin 27 receptor, alpha (Il27ra), interleukin 27 receptor subunit alpha (Il27ra), CRL1, IL-27R, IL-27RA, IL27R, IL27RA, TCCR, Tccr, WSX-1, WSX1, Wsx1, zcytor1

Protein level used designations for IL27 Receptor alpha

  • interleukin 27 receptor, alpha
  • class I cytokine receptor
  • interleukin-27 receptor subunit alpha
  • type-I T cell cytokine receptor
  • IL-27 receptor subunit alpha
  • IL-27R subunit alpha
  • IL-27R-alpha
  • T-cell cytokine receptor type 1
  • cytokine receptor WSX-1
  • cytokine receptor-like 1
  • type I T-cell cytokine receptor
  • IL-27RA
  • T cell cytokine receptor
  • T cell cytokine receptor; cytokine receptor family, class 1 (WSXWS), member 1
  • cytokine receptor family, class 1 (WSXWS), member 1
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