IL1RN Protéines
(Interleukin 1 Receptor Antagonist (IL1RN))
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
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Animal-Free
IL1RN
Origine: Humain, Souris
Hôte: HEK-293 Cells
Recombinant
>95 % (SDS-PAGE)
IL1RN
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 97 % as determined by reducing SDS-PAGE.
Active
IL1RN
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 %
Inactive
IL1RN
Origine: Macaque rhésus
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
IL1RN
Origine: Lapin
Hôte: Escherichia coli (E. coli)
Recombinant
> 97 %
WB, SDS, Imm, PC
IL1RN
Origine: Porc
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
IL1RN
Origine: Chien
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
IL1RN
Origine: Boeuf (Vache)
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
IL1RN
Origine: Cheval
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
IL1RN
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
> 95% by SDS-PAGE
SDS, AcA
Active
IL1RN
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 95% by SDS - PAGE
SDS, AcA
Active
IL1RN
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
Inactive
IL1RN
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
> 95 %
Inactive
IL1RN
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by SDS-PAGE and Coomassie blue staining
Func, STD, AbP, PI
Active
1 image
IL1RN
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by SDS-PAGE and Coomassie blue staining
STD, AbP
1 image
IL1RN
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
STD, AbP
1 image
IL1RN
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
STD, AbP
1 image
IL1RN
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
STD, AbP
1 image
IL1RN
Origine: Chien
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, ELISA, IP
1 image
IL1RN
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 % , as determined by Coomassie stained SDS-PAGE.
ELISA, FACS
Active
Dernières publications pour nos IL1RN Protéines
: "Axl Deficiency Promotes the Neuroinvasion of Japanese Encephalitis Virus by Enhancing IL-1α Production from Pyroptotic Macrophages." dans: Journal of virology, Vol. 94, Issue 17, (2020) (PubMed).: "Inflammatory Human Umbilical Cord-Derived Mesenchymal Stem Cells Promote Stem Cell-Like Characteristics of Cancer Cells in an IL-1β-Dependent Manner." dans: BioMed research international, Vol. 2018, pp. 7096707, (2018) (PubMed).
: "The glucose-sensing transcription factor MLX promotes myogenesis via myokine signaling." dans: Genes & development, Vol. 29, Issue 23, pp. 2475-89, (2015) (PubMed).
: "Nod2-induced autocrine interleukin-1 alters signaling by ERK and p38 to differentially regulate secretion of inflammatory cytokines." dans: Gastroenterology, Vol. 143, Issue 6, pp. 1530-43, (2012) (PubMed).
: "Distinct roles for Nod2 protein and autocrine interleukin-1beta in muramyl dipeptide-induced mitogen-activated protein kinase activation and cytokine secretion in human macrophages." dans: The Journal of biological chemistry, Vol. 286, Issue 30, pp. 26440-9, (2011) (PubMed).
: "Interleukin-1 alpha blockade prevents hyperkeratosis in an in vitro model of lamellar ichthyosis." dans: Human molecular genetics, Vol. 19, Issue 13, pp. 2594-605, (2010) (PubMed).
: "Interleukin 1 receptor antagonist is a member of the interleukin 1 gene family: evolution of a cytokine control mechanism." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 12, pp. 5232-6, (1991) (PubMed).
: "Purification, cloning, expression and biological characterization of an interleukin-1 receptor antagonist protein." dans: Nature, Vol. 344, Issue 6267, pp. 633-8, (1990) (PubMed).
Pseudonymes pour IL1RN Protéines
interleukin 1 receptor antagonist (IL1RN) Protéinesinterleukin 1 receptor antagonist (Il1rn) Protéines
interleukin 1 receptor antagonist-like (IL1RNL) Protéines
DIRA Protéines
F630041P17Rik Protéines
ICIL-1RA Protéines
IL-1ra Protéines
IL-1RA Protéines
IL-1ra3 Protéines
IL-1RN Protéines
IL1F3 Protéines
IL1RA Protéines
IL1RN Protéines
IRAP Protéines
IRAP1 Protéines
MVCD4 Protéines
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- IL3RA Protéines
- IL4 Receptor Protéines
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