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Importin 9 Produits

(Importin 9 (IPO9))

Catégories

Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of H2B histone (By similarity), RPS7 and RPL18A. Prevents the cytoplasmic aggregation of RPS7 and RPL18A by shielding exposed basic domains. May also import H2A, H3, H4 histones (By similarity), RPL4 and RPL6.

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Catégories Importin 9 en vedette

Importin 9 Anticorps

High quality antibodies with extensive validation data.

Importin 9 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Importin 9 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, FACS, IHC (p)
Validations
  • (3)
N° du produit ABIN651754
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
N° du produit ABIN652440
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
  • (2)
N° du produit ABIN537307
Quantité 100 μg
Fiche technique Fiche technique

Importin 9 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6205253
Quantité 96 tests
Fiche technique Fiche technique

Importin 9 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
N° du produit ABIN3136831
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7422577
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3134611
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits Importin 9

Sharili, Kenny, Vartiainen, Connelly: "Nuclear actin modulates cell motility via transcriptional regulation of adhesive and cytoskeletal genes." dans: Scientific reports, Vol. 6, pp. 33893, (2016) (PubMed).

Zehorai, Seger: "Beta-like importins mediate the nuclear translocation of mitogen-activated protein kinases." dans: Molecular and cellular biology, Vol. 34, Issue 2, pp. 259-70, (2013) (PubMed).

Dopie, Skarp, Rajakylä, Tanhuanpää, Vartiainen: "Active maintenance of nuclear actin by importin 9 supports transcription." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 9, pp. E544-52, (2012) (PubMed).

Umeda, Nishitani, Nishimoto: "A novel nuclear protein, Twa1, and Muskelin comprise a complex with RanBPM." dans: Gene, Vol. 303, pp. 47-54, (2003) (PubMed).

Wang, Li, Messing, Wu: "Activation of Ras/Erk pathway by a novel MET-interacting protein RanBPM." dans: The Journal of biological chemistry, Vol. 277, Issue 39, pp. 36216-22, (2002) (PubMed).

Nishitani, Hirose, Uchimura, Nakamura, Umeda, Nishii, Mori, Nishimoto: "Full-sized RanBPM cDNA encodes a protein possessing a long stretch of proline and glutamine within the N-terminal region, comprising a large protein complex." dans: Gene, Vol. 272, Issue 1-2, pp. 25-33, (2001) (PubMed).

Synonymes et noms alternatifs relatifs à Importin 9

importin 9 (IPO9), importin 9 (Ipo9), importin 9 (ipo9), importin 9 L homeolog (ipo9.L), importin 9 (cnrP), RAN binding protein 9 (Ranbp9), RAN binding protein 9 L homeolog (ranbp9.L), RAN binding protein 9 (RANBP9), RAN binding protein 9 (ranbp9), 0710008K06Rik, AI845704, bpm-l, bpm90, C78347, cb457, DDBDRAFT_0205722, DDBDRAFT_0229883, DDB_0205722, DDB_0229883, Imp9, IPO9, MGC81741, mKIAA1192, Ranbp9, RanBP9, ranbp9, ranbp9-a, ranbp9-b, ranbp9b, RanBPM, RGD1561940, wu:fc23d12, zgc:66429, zgc:158650

Protein level used designations for Importin 9

  • importin-9
  • ran-binding protein 9
  • ranBP9
  • Ran binding protein 9
  • imp9a
  • imp9b
  • importin-9a
  • importin-9b
  • importin 9
  • importin-9-like
  • LOW QUALITY PROTEIN: ran-binding protein 9
  • ran-binding protein M
  • RAN binding protein 9 b
  • Ran-binding protein M
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