IMPDH2 Produits
(IMP (Inosine 5'-Monophosphate) Dehydrogenase 2 (IMPDH2))
Catégories
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008].
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Catégories IMPDH2 en vedette
IMPDH2 Anticorps
High quality antibodies with extensive validation data.
IMPDH2 Kits ELISA
Reliable ELISA kits for a wide range of species.
IMPDH2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
IMPDH2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IP, RNAi
Validations
- (1)
- (4)
N° du produit
ABIN561488
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
N° du produit
ABIN7156292
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (4)
N° du produit
ABIN2855167
Quantité
100 μL
Fiche technique
Fiche technique
IMPDH2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6967575
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6967574
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6956714
Quantité
96 tests
Fiche technique
Fiche technique
IMPDH2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1307895
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7123412
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3081915
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits IMPDH2
: "Myc-dependent purine biosynthesis affects nucleolar stress and therapy response in prostate cancer." dans: Oncotarget, Vol. 6, Issue 14, pp. 12587-602, (2015) (PubMed).: "IMPDH2 mediate radioresistance and chemoresistance in osteosarcoma cells." dans: European review for medical and pharmacological sciences, Vol. 18, Issue 20, pp. 3038-44, (2014) (PubMed).
: "A purine nucleotide biosynthesis enzyme guanosine monophosphate reductase is a suppressor of melanoma invasion." dans: Cell reports, Vol. 5, Issue 2, pp. 493-507, (2013) (PubMed).
: "Proteomic analysis of the effects of the immunomodulatory mycotoxin deoxynivalenol." dans: Proteomics, Vol. 11, Issue 10, pp. 1903-14, (2011) (PubMed).
: "Antiproliferative effects of AVN944, a novel inosine 5-monophosphate dehydrogenase inhibitor, in prostate cancer cells." dans: International journal of cancer, Vol. 123, Issue 10, pp. 2294-302, (2008) (PubMed).
: "Direct role of nucleotide metabolism in C-MYC-dependent proliferation of melanoma cells." dans: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 15, pp. 2392-400, (2008) (PubMed).
: "Prognostic significance of drug-regulated genes in high-grade osteosarcoma." dans: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 20, Issue 10, pp. 1085-94, (2007) (PubMed).
Synonymes et noms alternatifs relatifs à IMPDH2
inosine monophosphate dehydrogenase 2 (IMPDH2), IMP (inosine 5'-monophosphate) dehydrogenase 2 (impdh2.S), IMP (inosine 5'-monophosphate) dehydrogenase 2 (impdh2), inosine monophosphate dehydrogenase 2 (impdh2), inosine monophosphate dehydrogenase 2 (Impdh2), inosine 5'-phosphate dehydrogenase 2 (impdh2), cb635, imp2, IMPD, impd2, IMPD2, IMPD 2, impdh-ii, IMPDH-II, impdh2, IMPDH 2, wu:fb64g02, wu:fc43f09Protein level used designations for IMPDH2
- IMP (inosine monophosphate) dehydrogenase 2
- inosine monophosphate dehydrogenase 2
- IMP (inosine 5'-monophosphate) dehydrogenase 2
- hCG2002013-like
- inosine-5'-monophosphate dehydrogenase 2-like
- IMP oxireductase 2
- IMPD 2
- IMPDH 2
- inosine 5' phosphate dehydrogenase 2
- inosine monophosphate dehydrogenase type II
- inosine-5'-monophosphate dehydrogenase 2
- IMP dehydrogenase 2
- IMPDH-II
- inosine 5'-phosphate dehydrogenase 2
- inosine 5-monophosphate dehydrogenase 2
- IMP dehydrogenase type II
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