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ITGA2 Produits

(Integrin alpha 2 (ITGA2))
This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].

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Catégories ITGA2 en vedette

ITGA2 Anticorps

High quality antibodies with extensive validation data.

ITGA2 Kits ELISA

Reliable ELISA kits for a wide range of species.

ITGA2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

ITGA2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application FACS, WB, IHC, ELISA, ICC, Neut
Validations
  • (5)
N° du produit ABIN5684082
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
  • (4)
N° du produit ABIN561540
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
N° du produit ABIN7433282
Quantité 100 μL
Fiche technique Fiche technique

ITGA2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (6)
N° du produit ABIN6720453
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6973617
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6956838
Quantité 96 tests
Fiche technique Fiche technique

ITGA2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1308165
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3093162
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3135560
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits ITGA2

Yun, Guan, Liu, Zhang, Wang, Qi, Cui, Liu, Zhang, Gao, Gao, Li, Gao, Wang: "Integrin αvβ1 Modulation Affects Subtype B Avian Metapneumovirus Fusion Protein-mediated Cell-Cell Fusion and Virus Infection." dans: The Journal of biological chemistry, Vol. 291, Issue 28, pp. 14815-25, (2016) (PubMed).

Stawikowski, Aukszi, Stawikowska, Cudic, Fields: "Glycosylation modulates melanoma cell α2β1 and α3β1 integrin interactions with type IV collagen." dans: The Journal of biological chemistry, Vol. 289, Issue 31, pp. 21591-604, (2014) (PubMed).

Albert, Veréb, Csomós, Moe, Johnsen, Olstad, Nicolaissen, Rajnavölgyi, Fésüs, Berta, Petrovski: "Cultivation and characterization of cornea limbal epithelial stem cells on lens capsule in animal material-free medium." dans: PLoS ONE, Vol. 7, Issue 10, pp. e47187, (2012) (PubMed).

Haglund, Tillgren, Addis, Wenglén, Recklies, Heinegård: "Identification and characterization of the integrin alpha2beta1 binding motif in chondroadherin mediating cell attachment." dans: The Journal of biological chemistry, Vol. 286, Issue 5, pp. 3925-34, (2011) (PubMed).

Eaton, Colombel, van der Pluijm, Cecchini, Wetterwald, Lippitt, Rehman, Hamdy, Thalman: "Evaluation of the frequency of putative prostate cancer stem cells in primary and metastatic prostate cancer." dans: The Prostate, Vol. 70, Issue 8, pp. 875-82, (2010) (PubMed).

Tanaka, Toujima, Toyoda, Takeuchi, Umesaki: "Establishment and characterization of novel human uterine leiomyosarcoma cell lines." dans: International journal of oncology, Vol. 37, Issue 1, pp. 125-31, (2010) (PubMed).

Nonaka, Saga, Fujiwara, Akimoto, Yamada, Kagawa, Takei, Machida, Takikawa, Suzuki: "Indoleamine 2,3-dioxygenase promotes peritoneal dissemination of ovarian cancer through inhibition of natural killercell function and angiogenesis promotion." dans: International journal of oncology, Vol. 38, Issue 1, pp. 113-20, (2010) (PubMed).

Tanaka, Wang, Umesaki: "Remodeling of the human endometrial epithelium is regulated by laminin and type IV collagen." dans: International journal of molecular medicine, Vol. 23, Issue 2, pp. 173-80, (2009) (PubMed).

Siegemund, Schütze, Schulz, Wolk, Nasilowska, Straubinger, Sabat, Alber: "Differential IL-23 requirement for IL-22 and IL-17A production during innate immunity against Salmonella enterica serovar Enteritidis." dans: International immunology, Vol. 21, Issue 5, pp. 555-65, (2009) (PubMed).

Lin, Chuang, Liao, Huang, Pai, Chu: "Combined immunogene therapy of IL-6 and IL-15 enhances anti-tumor activity through augmented NK cytotoxicity." dans: Cancer letters, Vol. 272, Issue 2, pp. 285-95, (2008) (PubMed).

Synonymes et noms alternatifs relatifs à ITGA2

integrin subunit alpha 2 (ITGA2), integrin alpha 2 (Itga2), integrin subunit alpha 2 (Itga2), BR, CD49B, DX5, GPIa, HPA-5, VLA-2, VLAA2

Protein level used designations for ITGA2

  • CD49 antigen-like family member B
  • VLA2 receptor, alpha-2 subunit
  • collagen receptor
  • human platelet alloantigen system 5
  • integrin alpha-2
  • platelet antigen Br
  • platelet glycoprotein GPIa
  • platelet membrane glycoprotein Ia
  • very late activation protein 2 receptor, alpha-2 subunit
  • GPIa
  • VLA-2 receptor, alpha 2 subunit
  • VLA-2 subunit alpha
  • VLA-2 alpha chain
  • LOW QUALITY PROTEIN: integrin alpha-2
  • integrin alpha 2 subunit
  • integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
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