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Kallikrein 7 Produits

(Kallikrein 7 (KLK7))

Catégories

This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011].

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Catégories Kallikrein 7 en vedette

Kallikrein 7 Anticorps

High quality antibodies with extensive validation data.

Kallikrein 7 Kits ELISA

Reliable ELISA kits for a wide range of species.

Kallikrein 7 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Kallikrein 7 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
N° du produit ABIN652197
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (3)
N° du produit ABIN652198
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (1)
  • (2)
N° du produit ABIN2855653
Quantité 100 μL
Fiche technique Fiche technique

Kallikrein 7 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
N° du produit ABIN6957256
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6962041
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6957257
Quantité 96 tests
Fiche technique Fiche technique

Kallikrein 7 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN7196671
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1308870
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Human Cells
Validations
  • (1)
N° du produit ABIN7320700
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Kallikrein 7

Delaunay, Deschamps, Haddada, Walker, Soosaipillai, Soualmia, El Amri, Diamandis, Brattsand, Magdolen, Darmoul: "Aberrant expression of kallikrein-related peptidase 7 is correlated with human melanoma aggressiveness by stimulating cell migration and invasion." dans: Molecular oncology, Vol. 11, Issue 10, pp. 1330-1347, (2018) (PubMed).

Sheets, Massey, Cronk, Iafrati, Herman: "Matrix- and plasma-derived peptides promote tissue-specific injury responses and wound healing in diabetic swine." dans: Journal of translational medicine, Vol. 14, Issue 1, pp. 197, (2016) (PubMed).

McGovern, Meinert, de Veer, Hollier, Parker, Upton: "Attenuated kallikrein-related peptidase activity disrupts desquamation and leads to stratum corneum thickening in human skin equivalent models." dans: The British journal of dermatology, (2016) (PubMed).

Yu, Prassas, Dimitromanolakis, Diamandis: "Novel Biological Substrates of Human Kallikrein 7 Identified through Degradomics." dans: The Journal of biological chemistry, Vol. 290, Issue 29, pp. 17762-75, (2015) (PubMed).

Yamamoto, Yamamoto, Yamada, Hasegawa, Hongo, Oda, Amizuka: "Hertwig's epithelial root sheath cell behavior during initial acellular cementogenesis in rat molars." dans: Histochemistry and cell biology, Vol. 142, Issue 5, pp. 489-96, (2014) (PubMed).

Heiker, Klöting, Kovacs, Kuettner, Sträter, Schultz, Kern, Stumvoll, Blüher, Beck-Sickinger: "Vaspin inhibits kallikrein 7 by serpin mechanism." dans: Cellular and molecular life sciences : CMLS, Vol. 70, Issue 14, pp. 2569-83, (2013) (PubMed).

Ishida-Yamamoto, Deraison, Bonnart, Bitoun, Robinson, OBrien, Wakamatsu, Ohtsubo, Takahashi, Hashimoto, Dopping-Hepenstal, McGrath, Iizuka, Richard, Hovnanian: "LEKTI is localized in lamellar granules, separated from KLK5 and KLK7, and is secreted in the extracellular spaces of the superficial stratum granulosum." dans: The Journal of investigative dermatology, Vol. 124, Issue 2, pp. 360-6, (2005) (PubMed).

Planque, de Monte, Guyetant, Rollin, Desmazes, Panel, Lemarié, Courty: "KLK5 and KLK7, two members of the human tissue kallikrein family, are differentially expressed in lung cancer." dans: Biochemical and biophysical research communications, Vol. 329, Issue 4, pp. 1260-6, (2005) (PubMed).

Vasilopoulos, Cork, Murphy, Williams, Robinson, Duff, Ward, Tazi-Ahnini: "Genetic association between an AACC insertion in the 3'UTR of the stratum corneum chymotryptic enzyme gene and atopic dermatitis." dans: The Journal of investigative dermatology, Vol. 123, Issue 1, pp. 62-6, (2004) (PubMed).

Sumer, Ahmad, Al-Mouzan, Al-Awamy: "Interaction of alpha-thalassemia with other hemoglobinopathies in the eastern province of Saudi Arabia." dans: Birth defects original article series, Vol. 23, Issue 5A, pp. 343-7, (1988) (PubMed).

Synonymes et noms alternatifs relatifs à Kallikrein 7

kallikrein related-peptidase 7 (chymotryptic, stratum corneum) (Klk7), kallikrein-related peptidase 7 (Klk7), kallikrein related peptidase 7 (KLK7), kallikrein related peptidase 7 (Klk7), hK7, Prss6, PRSS6, SCCE

Protein level used designations for Kallikrein 7

  • kallikrein 7 (chymotryptic, stratum corneum)
  • kallikrein-7
  • protease, serine, 6
  • serine protease 6
  • stratum corneum chymotryptic enzyme
  • thymopsin
  • kallikrein related-peptidase 7 (chymotryptic, stratum corneum)
  • signal protein
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