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KARS Produits

(Lysyl-tRNA Synthetase (KARS))
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories KARS en vedette

KARS Anticorps

High quality antibodies with extensive validation data.

KARS Kits ELISA

Reliable ELISA kits for a wide range of species.

KARS Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

KARS recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (6)
N° du produit ABIN7268350
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (4)
  • (3)
N° du produit ABIN969226
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p), IF, ICC
Validations
  • (4)
N° du produit ABIN2855293
Quantité 100 μL
Fiche technique Fiche technique

KARS recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6957609
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6957610
Quantité 96 tests
Fiche technique Fiche technique

KARS recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1308352
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123818
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3095758
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits KARS

Guo, Ignatov, Musier-Forsyth, Schimmel, Yang: "Crystal structure of tetrameric form of human lysyl-tRNA synthetase: Implications for multisynthetase complex formation." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 7, pp. 2331-6, (2008) (PubMed).

Kaminska, Francin, Shalak, Mirande: "Role of HIV-1 Vpr-induced apoptosis on the release of mitochondrial lysyl-tRNA synthetase." dans: FEBS letters, Vol. 581, Issue 16, pp. 3105-10, (2007) (PubMed).

Kovaleski, Kennedy, Khorchid, Kleiman, Matsuo, Musier-Forsyth: "Critical role of helix 4 of HIV-1 capsid C-terminal domain in interactions with human lysyl-tRNA synthetase." dans: The Journal of biological chemistry, Vol. 282, Issue 44, pp. 32274-9, (2007) (PubMed).

Sampath, Mazumder, Seshadri, Gerber, Chavatte, Kinter, Ting, Dignam, Kim, Driscoll, Fox: "Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translation." dans: Cell, Vol. 119, Issue 2, pp. 195-208, (2004) (PubMed).

Sang Lee, Gyu Park, Park, Seol, Lee, Kim: "Interaction network of human aminoacyl-tRNA synthetases and subunits of elongation factor 1 complex." dans: Biochemical and biophysical research communications, Vol. 291, Issue 1, pp. 158-64, (2002) (PubMed).

Cen, Khorchid, Javanbakht, Gabor, Stello, Shiba, Musier-Forsyth, Kleiman: "Incorporation of lysyl-tRNA synthetase into human immunodeficiency virus type 1." dans: Journal of virology, Vol. 75, Issue 11, pp. 5043-8, (2001) (PubMed).

Tolkunova, Park, Xia, King, Davidson: "The human lysyl-tRNA synthetase gene encodes both the cytoplasmic and mitochondrial enzymes by means of an unusual alternative splicing of the primary transcript." dans: The Journal of biological chemistry, Vol. 275, Issue 45, pp. 35063-9, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à KARS

Lysyl-tRNA synthetase (LysRS), lysyl-tRNA synthetase (kars), lysyl-tRNA synthetase S homeolog (kars.S), lysyl-tRNA synthetase L homeolog (kars.L), lysyl-tRNA synthetase (Bm1_16500), lysyl-tRNA synthetase (lysS), Lysyl-tRNA synthetase (lysS), lysyl-tRNA synthetase (Taci_1118), lysyl-tRNA synthetase (Tpau_1737), lysyl-tRNA synthetase (Arch_0261), lysyl-tRNA synthetase (Trad_2960), lysyl-tRNA synthetase (Spirs_3699), lysyl-tRNA synthetase (KARS), lysyl-tRNA synthetase (LOC100280510), lysyl-tRNA synthetase (Tb927.6.1510), lysyl-tRNA synthetase (Kars), AA589550, AL024334, AL033315, AL033367, cb530, CG12141, CMTRIB, D8Ertd698e, D8Wsu108e, DFNB89, Dmel\\CG12141, kars, KARS, KARS1, kars2, KARS2, KRS, krs, krs-1, LysRS, MGC53345, mKIAA0070, Tb06.28P18.190, wu:fa16h02, zgc:92483

Protein level used designations for KARS

  • Aats-lys-PA
  • Aats-lys-PB
  • Aats-lys-PC
  • CG12141-PA
  • CG12141-PB
  • CG12141-PC
  • fa16h02
  • lysine--tRNA ligase
  • lysyl-tRNA synthetase
  • lysRS
  • lysine tRNA ligase
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