KCNJ3 Produits
(Potassium Inwardly-Rectifying Channel, Subfamily J, Member 3 (KCNJ3))
Catégories
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex that also couples to neurotransmitter receptors in the brain and whereby channel activation can inhibit action potential firing by hyperpolarizing the plasma membrane. These multimeric G-protein-gated inwardly-rectifying potassium (GIRK) channels may play a role in the pathophysiology of epilepsy, addiction, Down's syndrome, ataxia, and Parkinson's disease. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, May 2012].
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Catégories KCNJ3 en vedette
KCNJ3 Anticorps
High quality antibodies with extensive validation data.
KCNJ3 Kits ELISA
Reliable ELISA kits for a wide range of species.
KCNJ3 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
KCNJ3 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Monkey, Mouse
Application
WB, IF, IHC, FACS, IHC (p)
Validations
- (6)
N° du produit
ABIN1491310
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Mouse, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
- (2)
N° du produit
ABIN719741
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, IHC, ICC
Validations
- (3)
N° du produit
ABIN6262821
Quantité
100 μL
Fiche technique
Fiche technique
KCNJ3 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380445
Quantité
2 x 96 tests
Fiche technique
Fiche technique
KCNJ3 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN3082233
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN3120859
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3120858
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits KCNJ3
: "Chronic obstructive sleep apnea causes atrial remodeling in canines: mechanisms and implications." dans: Basic research in cardiology, Vol. 109, Issue 5, pp. 427, (2014) (PubMed).: "A novel KCNJ5-insT149 somatic mutation close to, but outside, the selectivity filter causes resistant hypertension by loss of selectivity for potassium." dans: The Journal of clinical endocrinology and metabolism, Vol. 99, Issue 9, pp. E1765-73, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à KCNJ3
potassium voltage-gated channel subfamily J member 3 (KCNJ3), potassium inwardly-rectifying channel, subfamily J, member 3 (Kcnj3), potassium voltage-gated channel subfamily J member 3 (Kcnj3), GIRK1, girk1, Kcnf3, KGA, KIR3.1, Kir3.1Protein level used designations for KCNJ3
- G protein-activated inward rectifier potassium channel 1
- GIRK-1
- inward rectifier K(+) channel Kir3.1
- inward rectifier K+ channel KIR3.1
- potassium channel, inwardly rectifying subfamily J member 3
- potassium inwardly-rectifying channel subfamily J member 3 splice variant 1e
- potassium inwardly-rectifying channel J3
- GIRK1
- KGA
- KGB1
- potassium channel inwarding rectifying channel subfamily J member 3
- potassium channel subunit Kir3.1 type 3 delta
- inward rectifying potassium channel, Kir3.1
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