KDM2A Produits
(Lysine (K)-Specific Demethylase 2A (KDM2A))
Catégories
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012].
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Catégories KDM2A en vedette
KDM2A Anticorps
High quality antibodies with extensive validation data.
KDM2A Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
KDM2A recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
N° du produit
ABIN387896
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
N° du produit
ABIN7193407
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
ELISA, IHC
Validations
- (2)
N° du produit
ABIN7244933
Quantité
200 μL
Fiche technique
Fiche technique
KDM2A recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6228355
Quantité
96 tests
Fiche technique
Fiche technique
KDM2A recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7123806
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1353718
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3093402
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits KDM2A
: "HPV16 E7-induced upregulation of KDM2A promotes cervical cancer progression by regulating miR-132-radixin pathway." dans: Journal of cellular physiology, (2018) (PubMed).: "Transcriptional repression of histone deacetylase 3 by the histone demethylase KDM2A is coupled to tumorigenicity of lung cancer cells." dans: The Journal of biological chemistry, Vol. 289, Issue 11, pp. 7483-96, (2014) (PubMed).
: "KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling." dans: The Journal of clinical investigation, Vol. 123, Issue 12, pp. 5231-46, (2013) (PubMed).
: "Histone demethylation by a family of JmjC domain-containing proteins." dans: Nature, Vol. 439, Issue 7078, pp. 811-6, (2006) (PubMed).
: "Nucleolar proteome dynamics." dans: Nature, Vol. 433, Issue 7021, pp. 77-83, (2005) (PubMed).
: "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." dans: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 6, Issue 1, pp. 63-70, (1999) (PubMed).
Synonymes et noms alternatifs relatifs à KDM2A
lysine demethylase 2A (KDM2A), lysine (K)-specific demethylase 2A (Kdm2a), lysine demethylase 2A (Kdm2a), lysine (K)-specific demethylase 2Aa (kdm2aa), 5530401A10Rik, 100043628, AA589516, AW536790, Cxxc8, CXXC8, fb76b11, Fbl7, FBL7, Fbl11, FBL11, FBXL11, Fbxl11, Gm4560, Jhdm1, JHDM1A, Jhdm1a, KDM2A, lalina, LILINA, wu:fb76b11, wu:fj11c04, zgc:158441, zgc:158606Protein level used designations for KDM2A
- F-box and leucine-rich repeat protein 11
- jumonji C domain-containing histone demethylase 1A
- lysine-specific demethylase 2A
- F-box protein containing leucine repeats
- F-box/LRR-repeat protein 11
- [Histone-H3]-lysine-36 demethylase 1A
- jmjC domain-containing histone demethylation protein 1A
- lysine (K)-specific demethylase 2A
- CXXC-type zinc finger protein 8
- JmjC domain-containing histone demethylation protein 1B
- lysine (K)-specific demethylase 2B
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