KEAP1 Produits
(Kelch-Like ECH-Associated Protein 1 (KEAP1))
Catégories
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories KEAP1 en vedette
KEAP1 Anticorps
High quality antibodies with extensive validation data.
KEAP1 Kits ELISA
Reliable ELISA kits for a wide range of species.
KEAP1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
KEAP1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, FACS, ICC
Validations
- (2)
- (5)
N° du produit
ABIN1098137
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, FACS
Validations
- (2)
- (5)
N° du produit
ABIN1098141
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC, IHC (p), FACS
Validations
- (8)
N° du produit
ABIN1499016
Quantité
100 μL
Fiche technique
Fiche technique
KEAP1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
N° du produit
ABIN6957270
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6968103
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6975693
Quantité
96 tests
Fiche technique
Fiche technique
KEAP1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1308530
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (21)
- (1)
N° du produit
ABIN2724103
Quantité
20 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7123669
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits KEAP1
: "Cannabidiol Regulates the Expression of Keratinocyte Proteins Involved in the Inflammation Process through Transcriptional Regulation." dans: Cells, Vol. 8, Issue 8, (2020) (PubMed).: "Schisandrin C targets Keap1 and attenuates oxidative stress by activating Nrf2 pathway in Ang II-challenged vascular endothelium." dans: Phytotherapy research : PTR, Vol. 33, Issue 3, pp. 779-790, (2019) (PubMed).
: "Brusatol Enhances the Chemotherapy Efficacy of Gemcitabine in Pancreatic Cancer via the Nrf2 Signalling Pathway." dans: Oxidative medicine and cellular longevity, Vol. 2018, pp. 2360427, (2018) (PubMed).
: "Targeting the proinflammatory cytokines, oxidative stress, apoptosis and TGF-β1/STAT-3 signaling by irbesartan to ameliorate doxorubicin-induced hepatotoxicity." dans: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, Vol. 24, Issue 8, pp. 623-631, (2018) (PubMed).
: "Ameliorative potential of linagliptin and/or calcipotriol on bleomycin-induced lung fibrosis: In vivo and in vitro study." dans: Environmental toxicology and pharmacology, Vol. 50, pp. 216-226, (2017) (PubMed).
: "The electrophilic character of quinones is essential for the suppression of Bach1." dans: Toxicology, Vol. 387, pp. 17-26, (2017) (PubMed).
: "Selenium antagonizes cadmium-induced apoptosis in chicken spleen but not involving Nrf2-regulated antioxidant response." dans: Ecotoxicology and environmental safety, Vol. 145, pp. 503-510, (2017) (PubMed).
: "Induction of Mkp-1 and Nuclear Translocation of Nrf2 by Limonoids from Khaya grandifoliola C.DC Protect L-02 Hepatocytes against Acetaminophen-Induced Hepatotoxicity." dans: Frontiers in pharmacology, Vol. 8, pp. 653, (2017) (PubMed).
: "Caveolin-1 Expression Ameliorates Nephrotic Damage in a Rabbit Model of Cholesterol-Induced Hypercholesterolemia." dans: PLoS ONE, Vol. 11, Issue 4, pp. e0154210, (2016) (PubMed).
: "Rotavirus NSP1 Associates with Components of the Cullin RING Ligase Family of E3 Ubiquitin Ligases." dans: Journal of virology, Vol. 90, Issue 13, pp. 6036-48, (2016) (PubMed).
Synonymes et noms alternatifs relatifs à KEAP1
kelch like ECH associated protein 1 (KEAP1), kelch-like ECH-associated protein 1 (Keap1), Kelch-like ECH-associated protein 1 (Keap1), kelch-like ECH-associated protein 1a (keap1a), kelch like ECH associated protein 1 (keap1), kelch like ECH associated protein 1 L homeolog (keap1.L), kelch like ECH associated protein 1 (Keap1), kelch-like ECH-associated protein 1b (keap1b), fb36f11, INrf2, INRF2, Inrf2, keap1, KEAP1, KLHL19, klhl19, mKIAA0132, wu:fb36f11, zgc:171654Protein level used designations for KEAP1
- cytosolic inhibitor of Nrf2
- kelch-like family member 19
- kelch-like protein 19
- NRF2 cytosolic inhibitor
- ring canal protein
- kelch-like ECH-associated protein 1
- klhl19
- LOW QUALITY PROTEIN: kelch-like ECH-associated protein 1
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