SensoLyte® 440 Cathepsin B Assay Kit

N° du produit ABIN1882437

Aperçu rapide pour SensoLyte® 440 Cathepsin B Assay Kit (ABIN1882437)

Antigène: Cathepsin B (CTSB)

Méthode de détection: Fluorometric

Application: Fluorescence Resonance Energy Transfer Microscopy (FRET)

Détail du produit

Marque: SensoLyte®

Attributs du produit: The SensoLyte® 440 Cathepsin B Assay Kit provides a fluorogenic peptide for measurement of enzyme activity. This peptide releases the AMC (7-amino-4-methylcoumarin) fluorophore upon cathepsin B cleavage and can be detected with excitation at 354 nm and emission at 442 nm.

Information d'application

Commentaires:

FRET-based Assay Kit

Restrictions: For Research Use only

Stockage

Conseil sur la manipulation: Protect Components A and B from light and moisture.

Stock: -80 °C

Stockage commentaire: Store all kit components at -20 °C, except for Component C. Store Component C at -80 °C. Component D can be stored at room temperature for convenience

Référence

Vidal, Aguiar, Phansalkar, McAlpine, Napolitano, Chen, Araújo, Pauli, Bedran-Russo: "Galloyl moieties enhance the dentin biomodification potential of plant-derived catechins." dans: Acta biomaterialia, Vol. 10, Issue 7, pp. 3288-94, (2014) (PubMed).

Détail du antigène

Antigène: Cathepsin B (CTSB)

Autre désignation: Cathepsin B

Sujet: Cathepsins are a class of globular lysosomal proteases playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. The cathepsin family consists of 12 cysteine proteases with broad exo- and endopeptidase activity, of which Cathepsin B is a member. Elevated levels of cathepsin B were detected in metastases and neurological disorders including Alzheimer's disease (AD).