Cathepsin B Kit ELISA
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- Antigène Voir toutes Cathepsin B (CTSB) Kits ELISA
- Cathepsin B (CTSB)
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Reactivité
- Souris
- Méthode de détection
- Colorimetric
- Type de méthode
- Sandwich ELISA
- Gamme de detection
- 6-10000 pg/mL
- Seuil minimal de détection
- 6 pg/mL
- Application
- ELISA
- Marque
- BioAssay™
- Réactivité croisée (Details)
- There is no detectable cross-reactivity with other relevant proteins.
- Sensibilité
- < 5 pg/mL
- Ingrédients
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96-well plate pre-coated with anti-Cathepsin B, Mouse
Lyophilized recombinant Cathepsin B, Mouse standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL - Featured
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- Top Product
- Discover our top product CTSB Kit ELISA
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- Plaque
- Pre-coated
- Protocole
- Sandwich ELISA quantitative detection kit for Mouse Cathepsin B in cell culture supernates, serum and plasma (heparin, EDTA).Cathepsin B is an enzymatic protein belonging to the peptidase or protease families. In humans, it is coded by the CTSB gene.1, 2 And this gene is mapped to chromosome 8p22.3 The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. Cathepsin B was once suspected as a candidate protease participating in the conversion of -amyloid precursor protein into the amyloid plaques found in Alzheimer's disease patients. However, this function is now known to be mediated by BACE1 protease. It is now thought that cathepsin B can degrade -amyloid precursor protein into harmless fragments. Thus, it is conceivable cathepsin B may play a pivotal role in the natural defense against Alzheimer's disease.4 Overexpression of cathepsin B has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. The standard product used in this kit is recombinant mouse Cathepsin B with the molecular mass of 37kD.
- Restrictions
- For Research Use only
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- Stock
- 4 °C/-20 °C
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- Antigène Voir toutes Cathepsin B (CTSB) Kits ELISA
- Cathepsin B (CTSB)
- Abstract
- CTSB Produits
- Synonymes
- APPS Kit ELISA, CPSB Kit ELISA, CB Kit ELISA, apps Kit ELISA, cpsb Kit ELISA, LOC692390 Kit ELISA, CTSB Kit ELISA, cathepsin B Kit ELISA, cathepsin B S homeolog Kit ELISA, CTSB Kit ELISA, Ctsb Kit ELISA, ctsb.S Kit ELISA, LOC692390 Kit ELISA
- ID gène
- 13030
- UniProt
- P10605
- Pathways
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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