Leptin Receptor Kit ELISA

N° du produit ABIN2042578

Kit ELISA Souris Leptin Receptor, test Colorimetric pour la quantification de Souris Leptin Receptor.

Aperçu rapide pour Leptin Receptor Kit ELISA (ABIN2042578)

Antigène: Leptin Receptor (LEPR)

Reactivité: Souris

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Gamme de detection: 6-10000 pg/mL

Application: ELISA

Détail du produit Leptin Receptor Kit ELISA

Seuil minimal de détection: 6 pg/mL

Réactivité croisée (Details): There is no detectable cross-reactivity with other relevant proteins.

Sensibilité: < 5 pg/mL

Ingrédients: 96-well plate pre-coated with anti-Leptin receptor, Mouse
Lyophilized recombinant Leptin receptor, Mouse standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL

Information d'application

Plaque: Pre-coated

Protocole: Sandwich ELISA quantitative detection kit for Mouse Leptin receptor in cell culture supernates, serum and plasma (heparin, EDTA).Leptin receptor (or Obese receptor, OBR) is a single membrane-spanning receptor most related to the gp130 signal-transducing component of the IL-6 receptor, the G-CSF receptor, and the LIF receptor. OB-R mRNA is expressed not only in choroid plexus, but also in several other tissues, including hypothalamus.1 Leptin acts through the leptin receptor, a single-transmembrane domain receptor of the cytokine-receptor family.2 Leptin controls energy balance and food intake through the leptin receptor in the hypothalamus of the brain, which suggests that some polymorphisms of the leptin receptor gene (LEPR) might contribute to obesity or obesity-related diseases.3 Leptin is also involved in the regulation of blood pressure through the leptin receptor.4

Restrictions: For Research Use only

Stockage

Stock: 4 °C/-20 °C

Détail du antigène

Antigène: Leptin Receptor (LEPR)

Autre désignation: Leptin Receptor

ID gène: 16847

UniProt: P48356

Pathways: Signalistation JAK/STAT, AMPK Signaling, Feeding Behaviour