Granulin Kit ELISA
Aperçu rapide pour Granulin Kit ELISA (ABIN2042639)
Antigène
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Méthode de détection
Type de méthode
Gamme de detection
Application
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Seuil minimal de détection
- 1.6 ng/mL
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Réactivité croisée (Details)
- There is no detectable cross-reactivity with other relevant proteins.
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Sensibilité
- < 50 pg/mL
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Ingrédients
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96-well plate pre-coated with anti-Progranulin, Human
Lyophilized recombinant Progranulin, Human standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL
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Plaque
- Pre-coated
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Protocole
- Sandwich ELISA quantitative detection kit for Human Progranulin in cell culture supernates, serum, plasma (heparin, EDTA), saliva and urine.Granulin, also known as Proepithelin (PEPI) is a protein that in humans is encoded by the GRN gene. This gene is mapped to 17q21.31. Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88kD precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6kD peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.
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Restrictions
- For Research Use only
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Stock
- 4 °C/-20 °C
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- Granulin (GRN)
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Autre désignation
- Progranulin
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Classe de substances
- Viral Protein
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ID gène
- 2896
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UniProt
- P28799
Antigène Voir toutes Granulin (GRN) Kits ELISA
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