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Granulin Kit ELISA

Ce kit ELISA Colorimetric est destiné à la mesure quantitative de Humain Granulin.
N° du produit ABIN2042639
1.121,25 €
Plus frais de livraison 40,00 € et TVA
96 tests
Destination: France
Envoi sous 20 à 26 jours ouvrables

Aperçu rapide pour Granulin Kit ELISA (ABIN2042639)

Antigène

Voir toutes Granulin (GRN) Kits ELISA
Granulin (GRN)

Reactivité

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Humain

Méthode de détection

Colorimetric

Type de méthode

Sandwich ELISA

Gamme de detection

1.6-100 ng/mL

Application

ELISA
  • Seuil minimal de détection

    1.6 ng/mL

    Réactivité croisée (Details)

    There is no detectable cross-reactivity with other relevant proteins.

    Sensibilité

    < 50 pg/mL

    Ingrédients

    96-well plate pre-coated with anti-Progranulin, Human
    Lyophilized recombinant Progranulin, Human standard, 10 ng/tube, 2Ea
    Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
    Sample diluent buffer, 30 mL
    Antibody diluent buffer, 10 mL
    ABC diluent buffer, 10 mL
    TMB color developing agent, 10 mL
    TMB stop solution, 10 mL
  • Plaque

    Pre-coated

    Protocole

    Sandwich ELISA quantitative detection kit for Human Progranulin in cell culture supernates, serum, plasma (heparin, EDTA), saliva and urine.Granulin, also known as Proepithelin (PEPI) is a protein that in humans is encoded by the GRN gene. This gene is mapped to 17q21.31. Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88kD precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6kD peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.

    Restrictions

    For Research Use only
  • Stock

    4 °C/-20 °C
  • Antigène Voir toutes Granulin (GRN) Kits ELISA

    Granulin (GRN)

    Autre désignation

    Progranulin

    Classe de substances

    Viral Protein

    ID gène

    2896

    UniProt

    P28799
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