Granulin Kit ELISA
Aperçu rapide pour Granulin Kit ELISA (ABIN2745482)
Antigène
Voir toutes Granulin (GRN) Kits ELISAReactivité
Méthode de détection
Type de méthode
Gamme de detection
Application
Type d'échantillon
-
-
Seuil minimal de détection
- 0.125 ng/mL
-
Analytical Method
- Quantitative
-
Specificité
- Detects mouse progranulin.
-
Réactivité croisée
- Souris
-
Aucune reactivité croisée
- Humain
-
Réactivité croisée (Details)
- Does not cross-react with human progranulin.
-
Sensibilité
- 60 pg/mL
-
Attributs du produit
- Progranulin (mouse) ELISA Kit
-
-
-
-
Plaque
- Pre-coated
-
Restrictions
- For Research Use only
-
-
-
Stock
- 4 °C
-
Stockage commentaire
-
Short Term Storage: +4°C
Long Term Storage: +4°C
12 months after the day of manufacturing. See expiry date on ELISA Kit box.
-
-
- Granulin (GRN)
-
Autre désignation
- Progranulin
-
Classe de substances
- Viral Protein
-
Sujet
- Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. New cutting-edge publications have shown that progranulin might be a biomarker not only for FTLD, but also for other types of Alzheimer's disease (AD). This new data even supposes the potential of progranulin to be a biomarker for MCI (Mild Cognitive Impairment), which would be a hallmark in AD research. Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis.
-
UniProt
- P28798
Antigène Voir toutes Granulin (GRN) Kits ELISA
-