IL1A Kit ELISA
Aperçu rapide pour IL1A Kit ELISA (ABIN4986937)
Antigène
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Méthode de détection
Type de méthode
Gamme de detection
Application
Type d'échantillon
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Seuil minimal de détection
- 1.8 pg/mL
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Analytical Method
- Quantitative
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Specificité
- Natural and recombinant Mouse IL-1a Ligand
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Sensibilité
- 1 pg/mL
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Matériel non inclus
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- Microplate reader.
- Pipettes and pipette tips.
- EP tube Deionized or distilled water.
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Indications d'application
- Detection Wavelength: 450 nm
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Volume d'échantillon
- 20 μL
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Durée du test
- 3 h
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Plaque
- Pre-coated
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Restrictions
- For Research Use only
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Stock
- 4 °C
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- IL1A (Interleukin 1 alpha (IL1A))
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Autre désignation
- IL-1a
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Sujet
- Interleukin-1 alpha(IL-1a) is a proinflammatory cytokine produced by a wide variety of cell types, including macrophages, osteoblasts, monocytes and hepatocytes. IL-1 alpha is synthesized as 31 kDa precursors that are subsequently cleaved into proteins with molecular weights of approximately 17 kDa. The IL-1a precursor reportedly shows full biological activity in the EL-4 assay. Circulating levels of IL-1a are normally low and only rise after stimulation by agents such as those produced byinflammation, infection or microbial endotoxins. IL-1a possesses a wide variety of biological activities and exerts its effects by binding to specific cell surface receptors.
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Pathways
- Signalisation NF-kappaB, Autophagy, Cancer Immune Checkpoints
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