IL-5 Kit ELISA
Aperçu rapide pour IL-5 Kit ELISA (ABIN4986959)
Antigène
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Méthode de détection
Type de méthode
Gamme de detection
Application
Type d'échantillon
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Seuil minimal de détection
- 3.9 pg/mL
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Analytical Method
- Quantitative
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Specificité
- Natural and recombinant Human IL-5 Ligand
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Sensibilité
- 2 pg/mL
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Matériel non inclus
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- Microplate reader.
- Pipettes and pipette tips.
- EP tube Deionized or distilled water.
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Indications d'application
- Detection Wavelength: 450 nm
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Volume d'échantillon
- 20 μL
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Durée du test
- 3 h
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Plaque
- Pre-coated
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Restrictions
- For Research Use only
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Stock
- 4 °C
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- IL-5 (IL5) (Interleukin 5 (IL5))
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Autre désignation
- IL-5
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Sujet
- Interleukin-5(IL-5)is a secreted glycoprotein that belongs to the α-helical group of cytokines (1-3). Unlike other family members, it is present as a covalently linked antiparallel dimer (4, 5). The cDNA for human IL-5 encodes a signal peptide and a 115 amino acid (aa) mature protein. Mature human IL-5 shares 70 % , 70 %, 62 %, 71 %, 70 % and 66 %, aa sequence identity with mouse, rat, canine, equine, feline and porcine IL-5, respectively and shows cross-reactivity with mouse IL-5. IL-5 is primarily produced by CD4+ Th2 cells, but also by activated eosinophils, mast cells, EBV-transformed B cells, Reed-Sternberg cells in Hodgkin
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Pathways
- Signalistation JAK/STAT, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
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