IGF2 Kit ELISA

N° du produit ABIN5510551

Ce kit ELISA Colorimetric est conçu pour la mesure quantitative de Hamster IGF2.

Aperçu rapide pour IGF2 Kit ELISA (ABIN5510551)

Antigène: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Épitope: AA 25-91

Reactivité: Hamster

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Application: ELISA

Détail du produit IGF2 Kit ELISA

Fonction: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Chinese hamster IGF-2

Marque: PicoKine™

Analytical Method: Quantitative

Specificité: Expression system for standard: E.coli
Immunogen sequence: A25-E91

Réactivité croisée (Details): There is no detectable cross-reactivity with IGF-1.

Attributs du produit:

Sequence similarities: Belongs to the insulin family.

Information d'application

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4 °C for 6 months, at -20 °C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Date de péremption: 12 months

Détail du antigène

Antigène: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Autre désignation: Igf2

Sujet:

Protein Function: The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development.

Background: Insulin-like growth factor II is also known as somatomedin A. IGF-2 is a member of the insulin family of polypeptide growth factors that is involved in development and growth. It is paternally expressed in the fetus and placenta. IGF-II is a mitogen for many cell types and an important modulator of muscle growth and differentiation. IGF-II gene is prevalently expressed during prenatal development and its gene activity is regulated by genomic imprinting, in that the allele inherited from the father is active and the allele inherited from the mother is inactive in most normal tissues. IGF-II appears to be induced by placental lactogen during prenatal development. It is a mediator of prolactin-induced alveologenesis, prolactin, IGF-2, and cyclin D1, all of which are overexpressed in breast cancers, are components of a developmental pathway in the mammary gland.

Synonyms: Insulin-like growth factor II,IGF-II,Multiplication-stimulating activity,MSA,Multiplication-stimulating polypeptide,Insulin-like growth factor II,Preptin,Igf2,Igf-2,

Full Gene Name: Insulin-like growth factor II

Cellular Localisation: Secreted.

UniProt: P01346

Pathways: Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation