Endothelin 1 Kit ELISA

N° du produit ABIN5510598

Kit ELISA Chien Endothelin 1, test Colorimetric pour la quantification de Chien Endothelin 1.

Aperçu rapide pour Endothelin 1 Kit ELISA (ABIN5510598)

Antigène: Endothelin 1 (EDN1)

Épitope: AA 53-73

Reactivité: Chien

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Application: ELISA

Détail du produit Endothelin 1 Kit ELISA

Fonction: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Dog Caninea Endothelin

Marque: PicoKine™

Analytical Method: Quantitative

Specificité: Expression system for standard: human peptide
Immunogen sequence: C53-W73

Réactivité croisée (Details): There is no detectable cross-reactivity with other relevant proteins.

Attributs du produit:

Sequence similarities: Belongs to the endothelin/sarafotoxin family.

Tissue Specificity: Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells. .

Information d'application

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4 °C for 6 months, at -20 °C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Date de péremption: 12 months

Détail du antigène

Antigène: Endothelin 1 (EDN1)

Autre désignation: EDN1

Sujet:

Protein Function: Endothelins are endothelium-derived vasoconstrictor peptides.

Background: The endothelins is a family of structurally and pharmacologically distinct peptides, which has been identified and sequenced in Dog Canineas. Three isoforms of Dog Caninea endothelin have been identified: endothelin-1, -2, and -3. Endothelin-1 is a potent, 21-amino acid vasoconstrictor peptide produced by vascular endothelial cells. Endothelins are 21-amino acid vasoconstricting peptides produced primarily in the endothelium having a key role in vascular homeostasis. Endothelins are implicated in vascular diseases of several organ systems, including the heart, general circulation and brain. Endothelins are proteins that constrict blood vessels and raise blood pressure. They are normally kept in balance by other mechanisms, but when they are over-expressed, they contribute to high blood pressure(hypertension) and heart disease.

Synonyms: Endothelin-1,Preproendothelin-1,PPET1,Endothelin-1,ET-1,Big endothelin-1,EDN1,

Full Gene Name: Endothelin-1

Cellular Localisation: Secreted.

UniProt: P05305

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size