SFRP5 Kit ELISA

N° du produit ABIN5510650

Ce kit ELISA Colorimetric est conçu pour la mesure quantitative de Humain SFRP5.

Aperçu rapide pour SFRP5 Kit ELISA (ABIN5510650)

Antigène: SFRP5 (Secreted Frizzled-Related Protein 5 (SFRP5))

Épitope: AA 30-317

Reactivité: Humain

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Application: ELISA

Détail du produit SFRP5 Kit ELISA

Fonction: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human SFRP5

Marque: PicoKine™

Analytical Method: Quantitative

Specificité: Expression system for standard: CHO
Immunogen sequence: E30-H317

Réactivité croisée (Details): There is no detectable cross-reactivity with other relevant proteins.

Attributs du produit:

Tissue Specificity: Highly expressed in the retinal pigment epithelium (RPE) and pancreas. Weak expression in heart, liver and muscle. .

Information d'application

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Date de péremption: 12 months

Détail du antigène

Antigène: SFRP5 (Secreted Frizzled-Related Protein 5 (SFRP5))

Autre désignation: SFRP5

Sujet:

Protein Function: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP5 may be involved in determining the polarity of photoreceptor, and perhaps, other cells in the retina.

Background: Secreted frizzled-related protein 5 is a protein that in humans is encoded by the SFRP5 gene. SFRP5 is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP5 and SFRP1 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP5 is highly expressed in the retinal pigment epithelium, and moderately expressed in the pancreas.

Synonyms: Secreted frizzled-related protein 5,sFRP-5,Frizzled-related protein 1b,FRP-1b,Secreted apoptosis-related protein 3,SARP-3,SFRP5,FRP1B, SARP3,

Full Gene Name: Secreted frizzled-related protein 5

Cellular Localisation: Secreted.

UniProt: Q5T4F7

Pathways: Signalisation WNT