KREMEN1 Kit ELISA

N° du produit ABIN5510702

Ce kit ELISA Souris KREMEN1 est un kit ELISA Colorimetric conçu pour quantifier Souris KREMEN1.

Aperçu rapide pour KREMEN1 Kit ELISA (ABIN5510702)

Antigène: KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))

Épitope: AA 20-395

Reactivité: Souris

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Application: ELISA

Détail du produit KREMEN1 Kit ELISA

Fonction: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse Kremen-1

Marque: PicoKine™

Analytical Method: Quantitative

Specificité: Expression system for standard: NSO
Immunogen sequence: A20-G395

Réactivité croisée (Details): There is no detectable cross-reactivity with other relevant proteins.

Attributs du produit:

Tissue Specificity: In the adult, widely expressed with high levels in heart, lung, kidney, skeletal muscle and testis. .

Information d'application

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Date de péremption: 12 months

Détail du antigène

Antigène: KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))

Autre désignation: Kremen1

Sujet:

Protein Function: Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling (By similarity). .

Background: Kremen protein 1 is a protein that in humans is encoded by the KREMEN1 gene. This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.

Synonyms: Kremen protein 1,Dickkopf receptor,Kringle domain-containing transmembrane protein 1,Kringle-containing protein marking the eye and the nose,Kremen1,Kremen,

Full Gene Name: Kremen protein 1

Cellular Localisation: Membrane, Single-pass type I membrane protein.

UniProt: Q99N43

Pathways: Signalisation WNT