IL6RA Kit ELISA

N° du produit ABIN6719752

Détail du produit IL6RA Kit ELISA

Antigène: IL6RA (Interleukin 6 Receptor, alpha (IL6RA))

Reactivité: Humain

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Gamme de detection: 31.2 pg/mL - 2000 pg/mL

Seuil minimal de détection: 31.2 pg/mL

Application: ELISA

Fonction: Sandwich ELISA for Quantitative Detection of Antigen

Type d'échantillon: Cell Culture Supernatant, Plasma (EDTA - heparin - citrate), Serum

Analytical Method: Quantitative

Attributs du produit:

Synonyms: CD126, CD126 antigen, Gp80, IL 6R 1, IL 6R alpha, IL-6 receptor subunit alpha, IL-6R 1, IL-6R subunit alpha, IL-6R-1, IL-6R-alpha, IL-6RA, Il6r, IL6R1, IL6RA, IL6RA_HUMAN, IL6Ralpha, Interleukin 6 receptor, Interleukin 6 receptor alpha chain, Interleukin-6 receptor subunit alpha, Membrane glycoprotein 80, MGC104991, OTTHUMP00000034320

Background: IL6R alpha(IL6RA) also known as CD126 or IL6R, is a type I cytokine receptor. The IL6 receptor is a protein complex consisting of a IL-6 receptor subunit(IL6R) and interleukin 6 signal transducer Glycoprotein 130. IL6R also denotes the human gene encoding this subunit. Alternatively spliced transcript variants encoding distinct isoforms have been reported. IL6R subunit is also shared by many other cytokines. Interleukin-6 receptor has been shown to interact with Interleukin 6 and Ciliary neurotrophic factor. Ligand binding did not appear to affect IL6R dimerization status. IL6R dimerization occurs both on the cell surface and in solution.

Gene Name: IL6R

Production: Natural and recombinant human IL-6R alpha. There is no detectable cross-reactivity with other relevant proteins.

Standard: Expression system for standard: sf21, Immunogen sequence: L20-D358

Information d'application

Indications d'application:

Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 2000pg/mL, 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.2pg/mL human IL-6R alpha standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum, plasma(heparin, EDTA, citrate) or urine to each empty well. It is recommended that each human IL-6R alpha standard solution and each sample be measured in duplicate.

Blood Product Anticoagulant: Heparin Sodium

ELISA Dilution: 31.2pg/mL-2000pg/mL

Volume d'échantillon: 100 μL

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: RT,4 °C,-20 °C

Stockage commentaire: Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.

Détail du antigène

Antigène: IL6RA (Interleukin 6 Receptor, alpha (IL6RA))

Autre désignation: IL-6R alpha (IL6RA Produits)

Synonymes: IL6R1 Kit ELISA, Il6ra Kit ELISA, CD126 Kit ELISA, IL-6R-1 Kit ELISA, IL-6RA Kit ELISA, IL6Q Kit ELISA, IL6RA Kit ELISA, IL6RQ Kit ELISA, gp80 Kit ELISA, IL-6R Kit ELISA, Il6r Kit ELISA, interleukin 6 receptor Kit ELISA, interleukin 6 receptor, alpha Kit ELISA, Il6r Kit ELISA, IL6R Kit ELISA, Il6ra Kit ELISA

ID gène: 3570

NCBI Accession: NP_000556

UniProt: A0N0L5

Pathways: Signalistation JAK/STAT, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints