CSF1R Kit ELISA

N° du produit ABIN6720221

Détail du produit CSF1R Kit ELISA

Antigène: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Reactivité: Humain

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Gamme de detection: 62.5 pg/mL - 4000 pg/mL

Seuil minimal de détection: 62.5 pg/mL

Application: ELISA

Fonction: Sandwich ELISA for Quantitative Detection of Antigen

Type d'échantillon: Cell Culture Supernatant, Plasma (EDTA - heparin), Serum

Analytical Method: Quantitative

Attributs du produit:

Synonyms: C FMS, CD 115, CD115, CD115 antigen, CFMS, Colony stimulating factor 1 receptor, CSF-1 receptor, CSF-1-R, CSF1R_HUMAN, CSFR, FIM2, FMS, FMS proto oncogene, FMS protooncogene, HDLS, M-CSF Receptor, M-CSF-R, Macrophage colony stimulating factor 1 receptor, Macrophage colony-stimulating factor 1 receptor, McDonough feline sarcoma viral (v fms) oncogene homolog, Oncogen FMS, Proto-oncogene c-Fms, V-FMS McDonough feline sarcoma viral oncogen homolog

Background: CSF1R(Colony stimulating factor 1 receptor),also known as M-CSFR and CD115, is a cell-surface protein encoded, in humans, by the CSF1R gene. The gene is located on long arm of chromosome 5(5q32) on the Crick(minus) strand. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. The encoded protein is a single pass type I membrane protein and acts as the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. Both CSF1R, and its ligand colony stimulating factor 1 play an important role in the development of the mammary gland and may be involved in the process of mammary gland carcinogenesis.

Gene Name: CSF1R

Production: Natural and recombinant human CSF1R. There is no detectable cross-reactivity with other relevant proteins.

Standard: Expression system for standard: NSO, Immunogen sequence: I20-E512

Information d'application

Indications d'application:

Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 4000pg/mL, 2000pg/mL,1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL human CSF1R standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum or plasma(heparin, EDTA) to each empty well. It is recommended that each human CSF1R standard solution and each sample be measured in duplicate.

Blood Product Anticoagulant: Heparin Sodium

ELISA Dilution: 62.5pg/mL-4000pg/mL

Volume d'échantillon: 100 μL

Plaque: Pre-coated

Restrictions: For Research Use only

Stockage

Stock: RT,4 °C,-20 °C

Stockage commentaire: Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.

Détail du antigène

Antigène: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Autre désignation: CSF1R - M-CSFR (CSF1R Produits)

Synonymes: AI323359 Kit ELISA, CD115 Kit ELISA, CSF-1R Kit ELISA, Csfmr Kit ELISA, Fim-2 Kit ELISA, Fms Kit ELISA, M-CSF-R Kit ELISA, M-CSFR Kit ELISA, C-FMS Kit ELISA, CSFR Kit ELISA, FIM2 Kit ELISA, FMS Kit ELISA, HDLS Kit ELISA, PDGFRB Kit ELISA, MGC89146 Kit ELISA, CSF-1-R Kit ELISA, c-fms Kit ELISA, mrfms Kit ELISA, CSF1 Kit ELISA, M-CSF Kit ELISA, csf1r Kit ELISA, fms Kit ELISA, panther Kit ELISA, colony stimulating factor 1 receptor Kit ELISA, macrophage colony-stimulating factor receptor Kit ELISA, colony stimulating factor 1 receptor, a Kit ELISA, Csf1r Kit ELISA, CSF1R Kit ELISA, m-csfr Kit ELISA, csf1r Kit ELISA, csf1ra Kit ELISA

ID gène: 1436

NCBI Accession: NP_001275634

UniProt: P07333

Pathways: Signalisation RTK, Inositol Metabolic Process, Cell-Cell Junction Organization