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Klotho Produits

(Klotho (KL))
This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss. [provided by RefSeq, Jul 2008].

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Catégories Klotho en vedette

Klotho Anticorps

High quality antibodies with extensive validation data.

Klotho Kits ELISA

Reliable ELISA kits for a wide range of species.

Klotho Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Klotho recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (7)
N° du produit ABIN7436549
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application IHC (p), IHC (fro), IF (p)
Validations
  • (1)
  • (4)
N° du produit ABIN681778
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (4)
N° du produit ABIN7436552
Quantité 100 μL
Fiche technique Fiche technique

Klotho recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (6)
  • (6)
N° du produit ABIN6730981
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (6)
  • (1)
N° du produit ABIN6957334
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6957335
Quantité 96 tests
Fiche technique Fiche technique

Klotho recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3131425
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3093511
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3118869
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits Klotho

Pawlak, Domaniewski, Znorko, Pawlak: "The use of LP533401 as a therapeutic option for renal osteodystrophy affects, renal calcium handling, vitamin D metabolism, and bone health in uremic rats." dans: Expert opinion on therapeutic targets, Vol. 23, Issue 4, pp. 353-364, (2020) (PubMed).

Rodrigues, Serralha, Lima, Punaro, Visona, Fernandes, Higa: "P2X7 siRNA targeted to the kidneys increases klotho and delays the progression of experimental diabetic nephropathy." dans: Purinergic signalling, Vol. 16, Issue 2, pp. 175-185, (2020) (PubMed).

Ma, Liu, Li, Jiang, Kong: "Klotho ameliorates the onset and progression of cataract via suppressing oxidative stress and inflammation in the lens in streptozotocin-induced diabetic rats." dans: International immunopharmacology, Vol. 85, pp. 106582, (2020) (PubMed).

Ma, Li, Jiang, Chu: "Expression of α-Klotho Is Downregulated and Associated with Oxidative Stress in the Lens in Streptozotocin-induced Diabetic Rats." dans: Current eye research, pp. 1-8, (2020) (PubMed).

Dalise, Cavalli, Ghuman, Wahlberg, Gerwig, Chisari, Ambrosio, Modo: "Biological effects of dosing aerobic exercise and neuromuscular electrical stimulation in rats." dans: Scientific reports, Vol. 7, Issue 1, pp. 10830, (2019) (PubMed).

Tan, Cai: "Is there a role for newer biomarkers in chronic kidney disease-mineral and bone disorder management?" dans: Nephrology (Carlton, Vic.), Vol. 22 Suppl 2, pp. 14-18, (2018) (PubMed).

Jaturakan, Buranakarl, Dissayabutra, Chaiyabutr, Kijtawornrat, Rungsipipat: "Changes of Klotho protein and Klotho mRNA expression in a hydroxy-L-proline induced hyperoxaluric rat model." dans: The Journal of veterinary medical science, Vol. 79, Issue 11, pp. 1861-1869, (2018) (PubMed).

Sahu, Mamiya, Shinde, Cheikhi, Winter, Vo, Stolz, Roginskaya, Tang, St Croix, Sanders, Franti, Van Houten, Rando, Barchowsky, Ambrosio: "Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration." dans: Nature communications, Vol. 9, Issue 1, pp. 4859, (2018) (PubMed).

Qian, Guo, Che, Guan, Wu, Lu, Zhu, Pang, Yan, Ni, Gu: "Klotho Reduces Necroptosis by Targeting Oxidative Stress Involved in Renal Ischemic-Reperfusion Injury." dans: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 45, Issue 6, pp. 2268-2282, (2018) (PubMed).

Mao, Wu, Yang, Xu, Wang: "Advanced maternal age impairs spatial learning capacity in young adult mouse offspring." dans: American journal of translational research, Vol. 10, Issue 3, pp. 975-988, (2018) (PubMed).

Synonymes et noms alternatifs relatifs à Klotho

klotho (KL), klotho (Kl), Klotho (Kl), klotho (kl), klotho (LOC100533542), alpha-kl, KL, LOC100223456

Protein level used designations for Klotho

  • secreted form of Klotho protein
  • klotho
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