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Kv1.4 Produits

(Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 4 (KCNA4))

Catégories

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the A-type potassium current class, the members of which may be important in the regulation of the fast repolarizing phase of action potentials in heart and thus may influence the duration of cardiac action potential.[provided by RefSeq, Mar 2011].

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Catégories Kv1.4 en vedette

Kv1.4 Anticorps

High quality antibodies with extensive validation data.

Kv1.4 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Kv1.4 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse, Rat
Application WB, IF, IHC, ICC, LCI
Validations
  • (4)
N° du produit ABIN7043526
Quantité 25 μL
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (3)
  • (1)
N° du produit ABIN1881472
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
N° du produit ABIN3043264
Quantité 100 μg
Fiche technique Fiche technique

Kv1.4 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969457
Quantité 96 tests
Fiche technique Fiche technique

Kv1.4 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1308390
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3093255
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3135407
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits Kv1.4

Mulholland, Spencer, Hu, Kroener, Chandler: "Neuroplasticity of A-type potassium channel complexes induced by chronic alcohol exposure enhances dendritic calcium transients in hippocampus." dans: Psychopharmacology, Vol. 232, Issue 11, pp. 1995-2006, (2015) (PubMed).

Lee, Royston, Vest, Ley, Lee, Bolton, Chung: "N-methyl-D-aspartate receptors mediate activity-dependent down-regulation of potassium channel genes during the expression of homeostatic intrinsic plasticity." dans: Molecular brain, Vol. 8, pp. 4, (2015) (PubMed).

Fan, Guan, Wang, Zhao, Zhang, Tiwari, Hoffman, Li, Tao: "Impaired neuropathic pain and preserved acute pain in rats overexpressing voltage-gated potassium channel subunit Kv1.2 in primary afferent neurons." dans: Molecular pain, Vol. 10, pp. 8, (2014) (PubMed).

Speca, Ogata, Mandikian, Bishop, Wiler, Eum, Wenzel, Doisy, Matt, Campi, Golub, Nerbonne, Hell, Trainor, Sack, Schwartzkroin, Trimmer: "Deletion of the Kv2.1 delayed rectifier potassium channel leads to neuronal and behavioral hyperexcitability." dans: Genes, brain, and behavior, Vol. 13, Issue 4, pp. 394-408, (2014) (PubMed).

Dufour, Woodhouse, Goaillard: "Somatodendritic ion channel expression in substantia nigra pars compacta dopaminergic neurons across postnatal development." dans: Journal of neuroscience research, Vol. 92, Issue 8, pp. 981-99, (2014) (PubMed).

Ovsepian, Steuber, Le Berre, OHara, OLeary, Dolly: "A defined heteromeric KV1 channel stabilizes the intrinsic pacemaking and regulates the output of deep cerebellar nuclear neurons to thalamic targets." dans: The Journal of physiology, Vol. 591, Issue Pt 7, pp. 1771-91, (2013) (PubMed).

Brewster, Lugo, Patil, Lee, Qian, Vanegas, Anderson: "Rapamycin reverses status epilepticus-induced memory deficits and dendritic damage." dans: PLoS ONE, Vol. 8, Issue 3, pp. e57808, (2013) (PubMed).

Zhao, Tang, Zhang, Atianjoh, Zhao, Liang, Wang, Guan, Kao, Tiwari, Gao, Hoffman, Cui, Li, Dong, Tao: "A long noncoding RNA contributes to neuropathic pain by silencing Kcna2 in primary afferent neurons." dans: Nature neuroscience, Vol. 16, Issue 8, pp. 1024-31, (2013) (PubMed).

Wang, Kim, Lv, Tempel, Yamoah: "Association of the Kv1 family of K+ channels and their functional blueprint in the properties of auditory neurons as revealed by genetic and functional analyses." dans: Journal of neurophysiology, Vol. 110, Issue 8, pp. 1751-64, (2013) (PubMed).

Jukkola, Lovett-Racke, Zamvil, Gu: "K+ channel alterations in the progression of experimental autoimmune encephalomyelitis." dans: Neurobiology of disease, Vol. 47, Issue 2, pp. 280-93, (2012) (PubMed).

Synonymes et noms alternatifs relatifs à Kv1.4

potassium voltage-gated channel subfamily A member 4 (KCNA4), potassium voltage-gated channel subfamily A member 4 (LOC100622932), potassium voltage-gated channel subfamily A member 4 S homeolog (kcna4.S), potassium voltage-gated channel subfamily A member 4 (Kcna4), potassium voltage-gated channel, shaker-related subfamily, member 4 (Kcna4), DKFZp459N0126, HBK4, HK1, HPCN2, HUKII, KCHAN, KCNA4, KCNA4L, KCNA8, KV1.4, Kv1.4, Kv4, PCN2, RHK1, RK3

Protein level used designations for Kv1.4

  • Kv1.4 voltage-gated potassium channel
  • potassium channel alpha subunit Kv1.4
  • potassium voltage-gated channel, shaker-related subfamily, member 4
  • potassium channel Shaker alpha subunit variant cKv1.4(m)
  • Kv1.4 potassium channel
  • RCK4
  • potassium voltage gated channel, shaker related subfamily, member 4
  • potassium voltage-gated channel subfamily A member 4
  • voltage-gated potassium channel subunit Kv1.4
  • cardiac potassium channel
  • fetal skeletal muscle potassium channel
  • potassium channel 2
  • rapidly inactivating potassium channel
  • shaker-related potassium channel Kv1.4
  • type A potassium channel
  • voltage-gated K(+) channel HuKII
  • voltage-gated potassium channel HBK4
  • voltage-gated potassium channel HK1
  • BAK4
  • potassium voltage-gated channel, shaker-related subfamily, memeber 4
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