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LUM Produits

(Lumican (LUM))

Catégories

This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. [provided by RefSeq, Jul 2008].

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Catégories LUM en vedette

LUM Anticorps

High quality antibodies with extensive validation data.

LUM Kits ELISA

Reliable ELISA kits for a wide range of species.

LUM Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

LUM recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, FACS, IHC (p)
Validations
  • (1)
  • (3)
N° du produit ABIN391881
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
N° du produit ABIN7433708
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
N° du produit ABIN391882
Quantité 400 μL
Fiche technique Fiche technique

LUM recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
N° du produit ABIN6957545
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
N° du produit ABIN6973974
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968359
Quantité 96 tests
Fiche technique Fiche technique

LUM recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (2)
  • (1)
N° du produit ABIN1309888
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Human Cells
Validations
  • (1)
N° du produit ABIN7320810
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123797
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits LUM

Barbariga, Vallone, Mosca, Bignami, Magagnotti, Fonteyne, Chiappori, Milanesi, Rama, Andolfo, Ferrari: "The role of extracellular matrix in mouse and human corneal neovascularization." dans: Scientific reports, Vol. 9, Issue 1, pp. 14272, (2019) (PubMed).

Zhao, Li, Xu, He, Cui, Lv: "Lumican alleviates hypertrophic scarring by suppressing integrin-FAK signaling." dans: Biochemical and biophysical research communications, Vol. 480, Issue 2, pp. 153-159, (2016) (PubMed).

Gu, Wan, Xue, Cheng, Zheng, Zhao, Fan, Han, Tong, Yao: "Lumican as a novel potential clinical indicator for acute aortic dissection: A comparative study, based on multi-slice computed tomography angiography." dans: Experimental and therapeutic medicine, Vol. 11, Issue 3, pp. 923-928, (2016) (PubMed).

Cappellesso, Millioni, Arrigoni, Simonato, Caroccia, Iori, Guzzardo, Ventura, Tessari, Fassina: "Lumican is overexpressed in lung adenocarcinoma pleural effusions." dans: PLoS ONE, Vol. 10, Issue 5, pp. e0126458, (2015) (PubMed).

Gasimli, Hickey, Yang, Li, dela Rosa, Nairn, Kulik, Dordick, Moremen, Dalton, Linhardt: "Changes in glycosaminoglycan structure on differentiation of human embryonic stem cells towards mesoderm and endoderm lineages." dans: Biochimica et biophysica acta, Vol. 1840, Issue 6, pp. 1993-2003, (2014) (PubMed).

Gasimli, Stansfield, Nairn, Liu, Paluh, Yang, Dordick, Moremen, Linhardt: "Structural remodeling of proteoglycans upon retinoic acid-induced differentiation of NCCIT cells." dans: Glycoconjugate journal, Vol. 30, Issue 5, pp. 497-510, (2013) (PubMed).

Barderas, Mendes, Torres, Bartolomé, López-Lucendo, Villar-Vázquez, Peláez-García, Fuente, Bonilla, Casal: "In-depth characterization of the secretome of colorectal cancer metastatic cells identifies key proteins in cell adhesion, migration, and invasion." dans: Molecular & cellular proteomics : MCP, Vol. 12, Issue 6, pp. 1602-20, (2013) (PubMed).

de Wit, Belt, Delis-van Diemen, Carvalho, Coupé, Stockmann, Bril, Beliën, Fijneman, Meijer: "Lumican and versican are associated with good outcome in stage II and III colon cancer." dans: Annals of surgical oncology, Vol. 20 Suppl 3, pp. S348-59, (2013) (PubMed).

Xia, Hong, Ye, Wang, Chen, Liu: "Label-free quantitative proteomic analysis of right ventricular remodeling in infant Tetralogy of Fallot patients." dans: Journal of proteomics, Vol. 84, pp. 78-91, (2013) (PubMed).

Gu, Cheng, Yao, Yin, Tong, Rao, Yen, Ku, Rao: "Quantitative proteomics analysis by isobaric tags for relative and absolute quantitation identified Lumican as a potential marker for acute aortic dissection." dans: Journal of biomedicine & biotechnology, Vol. 2011, pp. 920763, (2012) (PubMed).

Synonymes et noms alternatifs relatifs à LUM

lumican (LUM), lumican L homeolog (lum.L), lumican (lum), lumican (CpipJ_CPIJ010209), lumican (Lum), DKFZp468L1116, ldc, LDC, Ldc, MGC64527, slrr2d, SLRR2D, zgc:86661

Protein level used designations for LUM

  • lumican
  • zlum
  • Keratan sulfate proteoglycan lumican
  • KSPG lumican
  • keratan sulfate proteoglycan lumican
  • lumican proteoglycan
  • KSPG
  • corneal keratan sulfate proteoglycan 37B core protein
  • keratan sulfate proteoglycan
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