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MCAM Protéines

(Melanoma Cell Adhesion Molecule (MCAM))
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

23 Résultats

MCAM Origine: Souris Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7275301
 
MCAM Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Pubmed 1 reference
N° du produit ABIN1310514
 
MCAM Origine: Humain Hôte: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
N° du produit ABIN2752854
 
MCAM Origine: Souris Hôte: HEK-293 Cells Recombinant > 98 % as determined by SDS-PAGE
N° du produit ABIN7196965
 
MCAM Origine: Humain Hôte: Baculovirus infected Insect Cells Recombinant > 95% by SDS-PAGE SDS
N° du produit ABIN5855057
 
MCAM Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
N° du produit ABIN7490860
 
MCAM Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7505436
 
MCAM Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7505192
 
MCAM Origine: Rat Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7505548
 
MCAM Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7505639
 
MCAM Origine: Humain Hôte: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. SDS, WB, Imm, ELISA, AcA Active
N° du produit ABIN7607458
 
MCAM Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
N° du produit ABIN7394561
 
MCAM Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC
N° du produit ABIN7394564
 
MCAM Origine: Rat Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS, WB, Imm, PC
N° du produit ABIN7417588
 
MCAM Origine: Humain Hôte: Wheat germ Recombinant AP
N° du produit ABIN1330310
 
MCAM Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 95 % Inactive
N° du produit ABIN7669287
 
MCAM Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % Inactive
N° du produit ABIN7669288
 
MCAM Origine: Rat Hôte: Escherichia coli (E. coli) Recombinant > 95 % Inactive
N° du produit ABIN7669286
 
MCAM Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % Inactive
N° du produit ABIN7669285
 
MCAM Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % SDS
N° du produit ABIN5712730
 
  • Type Protein
    • Protein
  • Application
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • ELISA
    • Immunogen (Imm)
    • Positive Control (PC)
    • Affinity Purification (AP)
    • Activity Assay (AcA)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Protein Interaction (PI)
    • Standard (STD)
  • Réactivité
    • Human
    • Mouse
    • Rat
    • Cynomolgus
  • Cité dans publications
  • Images disponible
  • Carrier free only
  • Hote
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Wheat germ
    • Baculovirus infected Insect Cells
    • HEK-293T Cells
    • Mammalian Cells
    • Yeast
  • Epitope
    • AA 24-559
    • AA 1-559
    • AA 1-646
    • AA 151-350
    • AA 224-464
    • AA 24-560
    • AA 24-563
    • AA 24-646
    • AA 25-206
    • AA 323-560
    • AA 324-565
    • AA 341-563
    • AA 50-646
    • partial
  • Conjugué
    • His tag
    • GST tag
    • His-DYKDDDDK-Strep II Tag
    • Myc-DYKDDDDK Tag
    • Inconjugué
  • Type Proteine
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Activité biologique
    • Biologically Inactive
    • Biologically Active
  • Grade
    • MALS verified
  • Supplier
    • antibodies-online
    • ACROBiosystems
    • CUSABIO
    • OriGene
    • Signalway

Dernières publications pour nos MCAM Protéines

Gao, Zhang, Wang, Liu, He, Liu, Wang, Feng, Yang, Wang, Meng, Yan: "The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis." dans: Nature communications, Vol. 8, pp. 15279, (2018) (PubMed).

Luo, Duan, Qian, Feng, Wu, Wang, Feng, Yang, Qin, Yan: "Macrophagic CD146 promotes foam cell formation and retention during atherosclerosis." dans: Cell research, Vol. 27, Issue 3, pp. 352-372, (2017) (PubMed).

Tu, Zhang, Yan, Luo, Kong, Wen, Ye, Chen, Feng, Liu, Wu, Yan: "CD146 acts as a novel receptor for netrin-1 in promoting angiogenesis and vascular development." dans: Cell research, Vol. 25, Issue 3, pp. 275-87, (2015) (PubMed).

Keller, Kalt, Raab, Schachner, Mayrhofer, Kerjaschki, Hantusch: "Selection of scFv Antibody Fragments Binding to Human Blood versus Lymphatic Endothelial Surface Antigens by Direct Cell Phage Display." dans: PLoS ONE, Vol. 10, Issue 5, pp. e0127169, (2015) (PubMed).

Ishikawa, Wondimu, Oikawa, Ingerpuu, Virtanen, Patarroyo: "Monoclonal antibodies to human laminin ?4 chain globular domain inhibit tumor cell adhesion and migration on laminins 411 and 421, and binding of ?6?1 integrin and MCAM to ?4-laminins." dans: Matrix biology : journal of the International Society for Matrix Biology, Vol. 36, pp. 5-14, (2014) (PubMed).

Ye, Zhang, Tu, Sun, Liu, Lu, Feng, Yang, Liu, Yan: "Wnt5a uses CD146 as a receptor to regulate cell motility and convergent extension." dans: Nature communications, Vol. 4, pp. 2803, (2013) (PubMed).

Simon, Martin, Smith, Thaikoottathil, Bowler, Barenkamp, Chu: "Up-regulation of MUC18 in airway epithelial cells by IL-13: implications in bacterial adherence." dans: American journal of respiratory cell and molecular biology, Vol. 44, Issue 5, pp. 606-13, (2011) (PubMed).

Pseudonymes pour MCAM Protéines

melanoma cell adhesion molecule (MCAM) Protéines
melanoma cell adhesion molecule (Mcam) Protéines
melanoma cell adhesion molecule b (mcamb) Protéines
1-gicerin Protéines
AV025631 Protéines
CD146 Protéines
cd146 Protéines
CD149 Protéines
gicerin Protéines
id:ibd3512 Protéines
mcam Protéines
MCAM Protéines
MUC18 Protéines
Muc18 Protéines
s-endo Protéines
s-gicerin Protéines
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