MCAM Protéines
(Melanoma Cell Adhesion Molecule (MCAM))
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
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24 Résultats
MCAM
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
MCAM
Origine: Humain
Hôte: Wheat germ
Recombinant
WB, ELISA, AP, AA
1 image
1 reference
MCAM
Origine: Humain
Hôte: HEK-293T Cells
Recombinant
SDS, WB, ELISA, PI
2 images
MCAM
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
> 98 % as determined by SDS-PAGE
1 image
MCAM
Origine: Humain
Hôte: Baculovirus infected Insect Cells
Recombinant
> 95 %
SDS
1 image
MCAM
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
1 image
MCAM
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
MCAM
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
MCAM
Origine: Rat
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
MCAM
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
MCAM
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
MCAM
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
SDS, WB, Imm, PC
MCAM
Origine: Humain
Hôte: Mammalian Cells
Recombinant
>90 % as determined by SDS-PAGE.
SDS, WB, Imm, ELISA, AcA
Active
MCAM
Origine: Rat
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 %
SDS, WB, Imm, PC
MCAM
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
Inactive
MCAM
Origine: Rat
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
Inactive
MCAM
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 %
Inactive
MCAM
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
Inactive
MCAM
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 %
SDS
1 image
Dernières publications pour nos MCAM Protéines
: "The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis." dans: Nature communications, Vol. 8, pp. 15279, (2018) (PubMed).: "Macrophagic CD146 promotes foam cell formation and retention during atherosclerosis." dans: Cell research, Vol. 27, Issue 3, pp. 352-372, (2017) (PubMed).
: "CD146 acts as a novel receptor for netrin-1 in promoting angiogenesis and vascular development." dans: Cell research, Vol. 25, Issue 3, pp. 275-87, (2015) (PubMed).
: "Selection of scFv Antibody Fragments Binding to Human Blood versus Lymphatic Endothelial Surface Antigens by Direct Cell Phage Display." dans: PLoS ONE, Vol. 10, Issue 5, pp. e0127169, (2015) (PubMed).
: "Monoclonal antibodies to human laminin ?4 chain globular domain inhibit tumor cell adhesion and migration on laminins 411 and 421, and binding of ?6?1 integrin and MCAM to ?4-laminins." dans: Matrix biology : journal of the International Society for Matrix Biology, Vol. 36, pp. 5-14, (2014) (PubMed).
: "Wnt5a uses CD146 as a receptor to regulate cell motility and convergent extension." dans: Nature communications, Vol. 4, pp. 2803, (2013) (PubMed).
: "Up-regulation of MUC18 in airway epithelial cells by IL-13: implications in bacterial adherence." dans: American journal of respiratory cell and molecular biology, Vol. 44, Issue 5, pp. 606-13, (2011) (PubMed).
Pseudonymes pour MCAM Protéines
melanoma cell adhesion molecule (MCAM) Protéinesmelanoma cell adhesion molecule (Mcam) Protéines
melanoma cell adhesion molecule b (mcamb) Protéines
1-gicerin Protéines
AV025631 Protéines
CD146 Protéines
cd146 Protéines
CD149 Protéines
gicerin Protéines
id:ibd3512 Protéines
mcam Protéines
MCAM Protéines
MUC18 Protéines
Muc18 Protéines
s-endo Protéines
s-gicerin Protéines
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