MCAM Produits
(Melanoma Cell Adhesion Molecule (MCAM))
Catégories
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
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Catégories MCAM en vedette
MCAM Anticorps
High quality antibodies with extensive validation data.
MCAM Kits ELISA
Reliable ELISA kits for a wide range of species.
MCAM Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
MCAM recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
FACS, IHC, WB, ELISA
Validations
- (2)
- (7)
N° du produit
ABIN1724844
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human
Application
FACS, WB, IF, ELISA
Validations
- (7)
N° du produit
ABIN7147325
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
IHC, WB, IF
Validations
- (7)
N° du produit
ABIN6143621
Quantité
100 μL
Fiche technique
Fiche technique
MCAM recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6962587
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (4)
- (1)
N° du produit
ABIN6960653
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6960654
Quantité
96 tests
Fiche technique
Fiche technique
MCAM recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN7275297
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
N° du produit
ABIN7275301
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1310514
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits MCAM
: "Epithelial-Mesenchymal Transition in Asthma Airway Remodeling Is Regulated by the IL-33/CD146 Axis." dans: Frontiers in immunology, Vol. 11, pp. 1598, (2020) (PubMed).: "Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice." dans: Redox biology, Vol. 24, pp. 101192, (2019) (PubMed).
: "The Role of MicroRNA-143-5p in the Differentiation of Dental Pulp Stem Cells into Odontoblasts by Targeting Runx2 via the OPG/RANKL Signaling Pathway." dans: Journal of cellular biochemistry, Vol. 119, Issue 1, pp. 536-546, (2018) (PubMed).
: "ImmunoPET Imaging of CD146 in Murine Models of Intrapulmonary Metastasis of Non-Small Cell Lung Cancer." dans: Molecular pharmaceutics, Vol. 14, Issue 10, pp. 3239-3247, (2018) (PubMed).
: "The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis." dans: Nature communications, Vol. 8, pp. 15279, (2018) (PubMed).
: "Sox10+adult stem cells contribute to biomaterial encapsulation and microvascularization." dans: Scientific reports, Vol. 7, pp. 40295, (2017) (PubMed).
: "The nitrobenzoxadiazole derivative MC3181 blocks melanoma invasion and metastasis." dans: Oncotarget, Vol. 8, Issue 9, pp. 15520-15538, (2017) (PubMed).
: "Macrophagic CD146 promotes foam cell formation and retention during atherosclerosis." dans: Cell research, Vol. 27, Issue 3, pp. 352-372, (2017) (PubMed).
: "Exendin-4 promotes proliferation of adipose-derived stem cells through ERK and JNK signaling pathways." dans: In vitro cellular & developmental biology. Animal, Vol. 52, Issue 5, pp. 598-606, (2016) (PubMed).
: "CD146 is a novel marker for highly tumorigenic cells and a potential therapeutic target in malignant rhabdoid tumor." dans: Oncogene, Vol. 35, Issue 40, pp. 5317-5327, (2016) (PubMed).
Synonymes et noms alternatifs relatifs à MCAM
melanoma cell adhesion molecule (MCAM), melanoma cell adhesion molecule (Mcam), melanoma cell adhesion molecule b (mcamb), 1-gicerin, AV025631, CD146, cd146, CD149, gicerin, id:ibd3512, mcam, MCAM, MUC18, Muc18, s-endo, s-gicerinProtein level used designations for MCAM
- Gicerin
- S-endo 1 endothelial-associated antigen
- cell surface glycoprotein MUC18
- cell surface glycoprotein P1H12
- melanoma adhesion molecule
- melanoma-associated antigen A32
- melanoma-associated antigen MUC18
- gicerin
- l-gicerin
- l-gicerin protein
- cell adhesion molecule
- HEMCAM
- melanoma cell adhesion molecule
- cell surface glycoprotein MUC18-like
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