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MCM6 Protéines

(Minichromosome Maintenance Complex Component 6 (MCM6))

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. Single nucleotide polymorphisms in the intron regions of this gene are associated with differential transcriptional activation of the promoter of the neighboring lactase gene and, thereby, influence lactose intolerance in early adulthood. [provided by RefSeq, May 2012].

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MCM6 Protein (AA 1-821) (His tag)

custom-made MCM6 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant MCM6 Protein, UniprotID Q14566

3 images

N° du produit ABIN7554505

Détails

MCM6 Protein (AA 1-821) (His tag)

custom-made MCM6 Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Mcm6 Protein, UniprotID P97311

3 images

N° du produit ABIN7563541

Détails

MCM6 Protein (AA 1-821) (GST tag)

MCM6 Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AP, AA

Image no. 1 for Minichromosome Maintenance Complex Component 6 (MCM6) (AA 1-821) protein (GST tag) (ABIN1310559)

1 image

1 reference

N° du produit ABIN1310559

Détails

MCM6 Protein (His tag)

MCM6 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant ELISA, WB, SDS

N° du produit ABIN7578112

Détails

MCM6 Protein (AA 557-821) (His-IF2DI Tag)

MCM6 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB

N° du produit ABIN7664651

Détails

MCM6 Protein (AA 1-821) (Strep Tag)

custom-made MCM6 Origine: Souris Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

N° du produit ABIN3134682

Détails

MCM6 Protein (AA 1-821) (Strep Tag)

custom-made MCM6 Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

N° du produit ABIN3093725