MECP2 Produits
(Methyl CpG Binding Protein 2 (MECP2))
Catégories
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. [provided by RefSeq, Jul 2009].
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Catégories MECP2 en vedette
MECP2 Anticorps
High quality antibodies with extensive validation data.
MECP2 Kits ELISA
Reliable ELISA kits for a wide range of species.
MECP2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
MECP2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC
Validations
- (8)
N° du produit
ABIN5542475
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human, Rat
Application
WB, IHC (p)
Validations
- (2)
- (4)
N° du produit
ABIN650833
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (5)
N° du produit
ABIN517816
Quantité
100 μg
Fiche technique
Fiche technique
MECP2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6962645
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6968595
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6960688
Quantité
96 tests
Fiche technique
Fiche technique
MECP2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1310622
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7123936
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1310624
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits MECP2
: "Linc-ROR promotes the progression of breast cancer and decreases the sensitivity to rapamycin through miR-194-3p targeting MECP2." dans: Molecular oncology, Vol. 14, Issue 9, pp. 2231-2250, (2021) (PubMed).: "Developmental nicotine exposure engenders intergenerational downregulation and aberrant posttranslational modification of cardinal epigenetic factors in the frontal cortices, striata, and hippocampi ..." dans: Epigenetics & chromatin, Vol. 13, Issue 1, pp. 13, (2020) (PubMed).
: "An electrochemiluminescence based assay for quantitative detection of endogenous and exogenously applied MeCP2 protein variants." dans: Scientific reports, Vol. 9, Issue 1, pp. 7929, (2020) (PubMed).
: "The significance of the increased expression of phosphorylated MeCP2 in the membranes from patients with proliferative diabetic retinopathy." dans: Scientific reports, Vol. 6, pp. 32850, (2018) (PubMed).
: "Expression of Phospho-MeCP2s in the Developing Rat Brain and Function of Postnatal MeCP2 in Cerebellar Neural Cell Development." dans: Neuroscience bulletin, Vol. 33, Issue 1, pp. 1-16, (2017) (PubMed).
: "CDYL suppresses epileptogenesis in mice through repression of axonal Nav1.6 sodium channel expression." dans: Nature communications, Vol. 8, Issue 1, pp. 355, (2017) (PubMed).
: "Whole Genome Expression Analysis in a Mouse Model of Tauopathy Identifies MECP2 as a Possible Regulator of Tau Pathology." dans: Frontiers in molecular neuroscience, Vol. 10, pp. 69, (2017) (PubMed).
: "Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior." dans: Nature neuroscience, Vol. 19, Issue 11, pp. 1497-1505, (2016) (PubMed).
: "MeCP2 SUMOylation rescues Mecp2-mutant-induced behavioural deficits in a mouse model of Rett syndrome." dans: Nature communications, Vol. 7, pp. 10552, (2016) (PubMed).
: "Geniposide alleviates inflammation by suppressing MeCP2 in mice with carbon tetrachloride-induced acute liver injury and LPS-treated THP-1 cells." dans: International immunopharmacology, (2015) (PubMed).
Synonymes et noms alternatifs relatifs à MECP2
methyl-CpG binding protein 2 (MECP2), methyl CpG binding protein 2 (Mecp2), methyl CpG binding protein 2 (mecp2), methyl-CpG binding protein 2 S homeolog (mecp2.S), 1500041B07Rik, AUTSX3, BB130002, D630021H01Rik, Mbd5, MRX16, MRX79, MRXS13, MRXSL, PPMX, RS, RTS, RTT, WBP10, wu:fk96a04, zgc:111857Protein level used designations for MECP2
- meCp-2 protein
- methyl-CpG-binding protein 2
- meCP-2 protein
- methyl-CpG-binding protein MeCP2
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