Mesothelin Protéines
(Mesothelin (MSLN))
This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010].
| Catalog no. | Produit | Reactivité | Hôte / Clonalité | Application | Prix et délai de livraison |
|---|---|---|---|---|---|
| Mesothelin Protein (MSLN) (AA 296-598) (Fc Tag) | Humain | HEK-293 Cells |
|
219,94 €
Voir le prix
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|
| Mesothelin Protein (MSLN) (AA 296-598) (His tag) | Humain | HEK-293 Cells |
|
197,38 €
Voir le prix
|
|
| Mesothelin Protein (MSLN) (AA 296-598) (His tag) | Cynomolgus | Human Cells |
|
1.974,03 €
Voir le prix
|
|
| Mesothelin Protein (MSLN) (AA 298-600) (His tag) | Souris | Human Cells |
|
230,69 €
Voir le prix
|
|
| Mesothelin Protein (MSLN) (AA 1-375) (Strep Tag) | Humain | Cell-free protein synthesis (CFPS) |
|
à partir de 15.754,29 €
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|
|
| Mesothelin Protein (MSLN) (AA 1-375) (Strep Tag) | Souris | Cell-free protein synthesis (CFPS) |
|
à partir de 15.754,29 €
Voir le prix
|
|
| Mesothelin Protein (MSLN) (Fc Tag,His tag) | Humain | HEK-293 Cells |
|
305,00 €
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|
|
| Mesothelin Protein (MSLN) | Humain | Mammalian Cells |
|
5.115,38 €
Voir le prix
|
|
| Mesothelin Protein (MSLN) (AA 296-591) (His tag) | Humain | HEK-293 Cells |
|
397,11 €
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|
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| Mesothelin Protein (MSLN) (AA 488-600) (hFc Tag) | Humain | HEK-293 Cells |
|
430,16 €
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|
|
| Mesothelin Protein (MSLN) (AA 296-580) (His-Avi Tag,PE) | Humain | HEK-293 Cells |
|
1.041,60 €
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|
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| Mesothelin Protein (MSLN) (AA 296-600) (Biotin,His-Avi Tag) | Humain | HEK-293 Cells |
|
628,47 €
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|
|
| Mesothelin Protein (MSLN) (AA 298-600) (His tag) | Rat | HEK-293 Cells |
|
397,11 €
Voir le prix
|
|
| Mesothelin Protein (MSLN) (His tag,Biotin,AVI tag) | Cynomolgus | HEK-293 Cells |
|
966,73 €
Voir le prix
|
|
| Mesothelin Protein (MSLN) (hFc-Avi Tag,Biotin) | Humain | HEK-293 Cells |
|
966,73 €
Voir le prix
|
|
| Mesothelin Protein (MSLN) (His tag,Biotin,AVI tag) | Souris | HEK-293 Cells |
|
966,73 €
Voir le prix
|
|
| Mesothelin Protein (MSLN) (His-Avi Tag,Biotin) | Humain | HEK-293 Cells |
|
966,73 €
Voir le prix
|
|
| Mesothelin Protein (MSLN) (AA 37-606) | Humain | Escherichia coli (E. coli) |
|
117,19 €
Voir le prix
|
|
| Mesothelin Protein (MSLN) (AA 34-514) (His tag) | Cynomolgus | HEK-293 Cells |
|
1.039,23 €
Voir le prix
|
|
| Mesothelin Protein (MSLN) (DYKDDDDK Tag,Strep Tag) | Humain | HEK-293 Cells |
|
8.130,77 €
Voir le prix
|
Protein
- Origine
- Humain
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
Protein
- Origine
- Humain
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
Protein
- Origine
- Cynomolgus
- Hôte
- Human Cells
- Type Proteine
- Recombinant
Protein
- Origine
- Souris
- Hôte
- Human Cells
- Type Proteine
- Recombinant
Protein
- WB (Western Blotting: Application indiquée)
- SDS (SDS-PAGE: Application indiquée)
- ELISA (ELISA: Application indiquée)
- Classe de qualité
- custom-made
- Origine
- Humain
- Hôte
- Cell-free protein synthesis (CFPS)
- Type Proteine
- Recombinant
- Pureté
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- WB (Western Blotting: Application indiquée)
- SDS (SDS-PAGE: Application indiquée)
- ELISA (ELISA: Application indiquée)
- Classe de qualité
- custom-made
- Origine
- Souris
- Hôte
- Cell-free protein synthesis (CFPS)
- Type Proteine
- Recombinant
- Pureté
- approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Protein
- Origine
- Humain
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- > 97 % by SDS-PAGE.
- Activité biologique
- Active
Protein
- Origine
- Humain
- Hôte
- Mammalian Cells
- Type Proteine
- Synthetic Nanodisc
Protein
- Origine
- Humain
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- Activité biologique
- Active
Protein
- Origine
- Humain
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- Activité biologique
- Active
Protein
- Origine
- Humain
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Activité biologique
- Active
Protein
- Origine
- Humain
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- Activité biologique
- Active
Protein
- Origine
- Rat
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
- Activité biologique
- Active
Protein
- Origine
- Cynomolgus
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- >95 % , as determined by SDS-PAGE and HPLC
Protein
- Origine
- Humain
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- >95 % , as determined by SDS-PAGE and HPLC
Protein
- Origine
- Souris
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- >95 % , as determined by SDS-PAGE and HPLC
Protein
- Origine
- Humain
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- >95 % , as determined by SDS-PAGE and HPLC
Protein
- Origine
- Humain
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- >95 % , as determined by SDS-PAGE and HPLC
Protein
- AM (Affinity Measurement: Application indiquée)
- ADA (Antibody Drug Assay: Application indiquée)
- IA (Immunoassay: Application indiquée)
- ScA (Screening Assay: Application indiquée)
- Origine
- Cynomolgus
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Protein
- ELISA (ELISA: Application indiquée)
- Imm (Immunogen: Application indiquée)
- cryo-EM (Cryogenic electron microscopy: Application indiquée)
- PhD (Phage Display: Application indiquée)
- SPR (Surface Plasmon Resonance: Application indiquée)
- Origine
- Humain
- Hôte
- HEK-293 Cells
- Type Proteine
- Synthetic Nanodisc
Dernières publications pour nos Mesothelin Protéines
: "Preclinical evaluation of a novel anti-mesothelin immunotoxin based on a single domain antibody as the targeting ligand." dans: International journal of pharmaceutics, Vol. 602, pp. 120647, (2021) (PubMed).
: "Engineered Fn3 protein has targeted therapeutic effect on mesothelin-expressing cancer cells and increases tumor cell sensitivity to chemotherapy." dans: Biotechnology and bioengineering, (2019) (PubMed).
: "Fn3 proteins engineered to recognize tumor biomarker mesothelin internalize upon binding." dans: PLoS ONE, Vol. 13, Issue 5, pp. e0197029, (2018) (PubMed).
: "Mesothelin enhances invasion of ovarian cancer by inducing MMP-7 through MAPK/ERK and JNK pathways." dans: The Biochemical journal, Vol. 442, Issue 2, pp. 293-302, (2012) (PubMed).
: "Mesothelin is a malignant factor and therapeutic vaccine target for pancreatic cancer." dans: Molecular cancer therapeutics, Vol. 7, Issue 2, pp. 286-96, (2008) (PubMed).
: "Engineered Fn3 protein has targeted therapeutic effect on mesothelin-expressing cancer cells and increases tumor cell sensitivity to chemotherapy." dans: Biotechnology and bioengineering, (2019) (PubMed).
: "Fn3 proteins engineered to recognize tumor biomarker mesothelin internalize upon binding." dans: PLoS ONE, Vol. 13, Issue 5, pp. e0197029, (2018) (PubMed).
: "Mesothelin enhances invasion of ovarian cancer by inducing MMP-7 through MAPK/ERK and JNK pathways." dans: The Biochemical journal, Vol. 442, Issue 2, pp. 293-302, (2012) (PubMed).
: "Mesothelin is a malignant factor and therapeutic vaccine target for pancreatic cancer." dans: Molecular cancer therapeutics, Vol. 7, Issue 2, pp. 286-96, (2008) (PubMed).
Pseudonymes pour Mesothelin Protéines
mesothelin (MSLN) Protéinesmesothelin (Msln) Protéines
mesothelin (LOC611363) Protéines
mesothelin (LOC100524016) Protéines
MPF Protéines
MSLN Protéines
SMRP Protéines
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