Mesothelin Produits
(Mesothelin (MSLN))
Catégories
This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010].
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Catégories Mesothelin en vedette
Mesothelin Anticorps
High quality antibodies with extensive validation data.
Mesothelin Kits ELISA
Reliable ELISA kits for a wide range of species.
Mesothelin Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Mesothelin recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
IHC (f)
Validations
- (7)
N° du produit
ABIN6939032
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, WB, FACS, IHC (p)
Validations
- (5)
N° du produit
ABIN727608
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, FACS
Validations
- (5)
N° du produit
ABIN6964068
Quantité
100 μg
Fiche technique
Fiche technique
Mesothelin recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6957762
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6957761
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6976025
Quantité
96 tests
Fiche technique
Fiche technique
Mesothelin recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (5)
N° du produit
ABIN7275282
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (5)
N° du produit
ABIN7275288
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
N° du produit
ABIN7275283
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Mesothelin
: "Preclinical evaluation of a novel anti-mesothelin immunotoxin based on a single domain antibody as the targeting ligand." dans: International journal of pharmaceutics, Vol. 602, pp. 120647, (2021) (PubMed).: "A liquid biopsy for detecting circulating mesothelial precursor cells: A new biomarker for diagnosis and prognosis in mesothelioma." dans: EBioMedicine, Vol. 61, pp. 103031, (2021) (PubMed).
: "Activated iNKT cells enhance the anti-tumor effect of antigen specific CD8 T cells on mesothelin-expressing salivary gland cancer." dans: BMC cancer, Vol. 18, Issue 1, pp. 1254, (2019) (PubMed).
: "Development of Anti-Human Mesothelin-Targeted Chimeric Antigen Receptor Messenger RNA-Transfected Peripheral Blood Lymphocytes for Ovarian Cancer Therapy." dans: Human gene therapy, Vol. 29, Issue 5, pp. 614-625, (2019) (PubMed).
: "Engineered Fn3 protein has targeted therapeutic effect on mesothelin-expressing cancer cells and increases tumor cell sensitivity to chemotherapy." dans: Biotechnology and bioengineering, (2019) (PubMed).
: "Recombination of a dual-CAR-modified T lymphocyte to accurately eliminate pancreatic malignancy." dans: Journal of hematology & oncology, Vol. 11, Issue 1, pp. 102, (2018) (PubMed).
: "Efficacy of Anti-mesothelin Immunotoxin RG7787 plus Nab-Paclitaxel against Mesothelioma Patient-Derived Xenografts and Mesothelin as a Biomarker of Tumor Response." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 23, Issue 6, pp. 1564-1574, (2018) (PubMed).
: "Live-Cell Mesothelioma Biobank to Explore Mechanisms of Tumor Progression." dans: Frontiers in oncology, Vol. 8, pp. 40, (2018) (PubMed).
: "Fn3 proteins engineered to recognize tumor biomarker mesothelin internalize upon binding." dans: PLoS ONE, Vol. 13, Issue 5, pp. e0197029, (2018) (PubMed).
: "Nucleoside reverse transcriptase inhibitor-induced rat oocyte dysfunction and low fertility mediated by autophagy." dans: Oncotarget, Vol. 9, Issue 3, pp. 3895-3907, (2018) (PubMed).
Synonymes et noms alternatifs relatifs à Mesothelin
mesothelin (MSLN), mesothelin (Msln), mesothelin (LOC611363), mesothelin (LOC100524016), MPF, MSLN, SMRPProtein level used designations for Mesothelin
- CAK1 antigen
- megakaryocyte potentiating factor
- pre-pro-megakaryocyte-potentiating factor
- soluble MPF mesothelin related protein
- ERC/mesothelin
- protein expressed in renal carcinoma
- mesothelin
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