MGLL Produits
(Monoglyceride Lipase (MGLL))
Catégories
This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012].
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Catégories MGLL en vedette
MGLL Anticorps
High quality antibodies with extensive validation data.
MGLL Kits ELISA
Reliable ELISA kits for a wide range of species.
MGLL Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
MGLL recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC, ELISA, FACS, IF
Validations
- (9)
N° du produit
ABIN334436
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (4)
N° du produit
ABIN2855646
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (3)
N° du produit
ABIN7160192
Quantité
100 μL
Fiche technique
Fiche technique
MGLL recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6968668
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6957875
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6975648
Quantité
96 tests
Fiche technique
Fiche technique
MGLL recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1310880
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124018
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7279205
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits MGLL
: "Hemisphere-dependent endocannabinoid system activity in prefrontal cortex and hippocampus of the Flinders Sensitive Line rodent model of depression." dans: Neurochemistry international, Vol. 125, pp. 7-15, (2019) (PubMed).: "Chemoproteomic, biochemical and pharmacological approaches in the discovery of inhibitors targeting human α/β-hydrolase domain containing 11 (ABHD11)." dans: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, Vol. 93, pp. 253-63, (2016) (PubMed).
: "YAP-mediated induction of monoacylglycerol lipase restrains oncogenic transformation." dans: Cellular signalling, Vol. 27, Issue 4, pp. 836-40, (2015) (PubMed).
: "The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 24, pp. E2472-81, (2014) (PubMed).
: "Mutation of Cys242 of human monoacylglycerol lipase disrupts balanced hydrolysis of 1- and 2-monoacylglycerols and selectively impairs inhibitor potency." dans: Molecular pharmacology, Vol. 85, Issue 3, pp. 510-9, (2014) (PubMed).
: "Robust hydrolysis of prostaglandin glycerol esters by human monoacylglycerol lipase (MAGL)." dans: Molecular pharmacology, Vol. 86, Issue 5, pp. 522-35, (2014) (PubMed).
: "Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12)." dans: Journal of lipid research, Vol. 53, Issue 11, pp. 2413-24, (2012) (PubMed).
: "The phospholipase A1 activity of lysophospholipase A-I links platelet activation to LPA production during blood coagulation." dans: Journal of lipid research, Vol. 52, Issue 5, pp. 958-70, (2011) (PubMed).
: "A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol." dans: Chemistry & biology, Vol. 14, Issue 12, pp. 1347-56, (2007) (PubMed).
Synonymes et noms alternatifs relatifs à MGLL
monoglyceride lipase (mgll), monoglyceride lipase (MGLL), monoglyceride lipase L homeolog (mgll.L), 13L protein (13L), monoglyceride lipase (YMTVg13L), Monoglyceride lipase (EHI_044210), Monoglyceride lipase (EHI_045330), monoglyceride lipase (TATV_DAH68_039), monoglyceride lipase (13L), monoglyceride lipase (Mgll), AA589436, cb909, hu-k5, HU-K5, HUK5, MAGL, Magl, MGC84195, mgl, MGL, Mgl, MGLL, mgll, wu:fc66g01, zgc:56561Protein level used designations for MGLL
- monoglyceride lipase
- Monoglyceride lipase
- lysophospholipase homolog
- monoacylglycerol lipase
- MGL
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