MGMT Produits
(O6-Methylguanine-DNA-Methyltransferase (MGMT))
Catégories
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a
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Catégories MGMT en vedette
MGMT Anticorps
High quality antibodies with extensive validation data.
MGMT Kits ELISA
Reliable ELISA kits for a wide range of species.
MGMT Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
MGMT recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, ELISA, FACS, ICC
Validations
- (7)
N° du produit
ABIN5542437
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Rat
Application
WB, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (1)
- (4)
N° du produit
ABIN730768
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, ICC, IP
Validations
- (4)
N° du produit
ABIN7434551
Quantité
100 μL
Fiche technique
Fiche technique
MGMT recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6958286
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969037
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958287
Quantité
96 tests
Fiche technique
Fiche technique
MGMT recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124248
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1310882
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1310884
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits MGMT
: "Effects of Some Growth Factors and Cytokines on the Expression of the Repair Enzyme MGMT and Protein MARP in Human Cells In Vitro : Effect of Some Growth Factors and Cytokines." dans: Biochemical genetics, Vol. 56, Issue 5, pp. 459-477, (2018) (PubMed).: "PLK1 inhibition enhances temozolomide efficacy in IDH1 mutant gliomas." dans: Oncotarget, Vol. 8, Issue 9, pp. 15827-15837, (2017) (PubMed).
: "MGMT gene variants, temozolomide myelotoxicity and glioma risk. A concise literature survey including an illustrative case." dans: Journal of chemotherapy (Florence, Italy), Vol. 29, Issue 4, pp. 238-244, (2017) (PubMed).
: "Akt and β-catenin contribute to TMZ resistance and EMT of MGMT negative malignant glioma cell line." dans: Journal of the neurological sciences, Vol. 367, pp. 101-6, (2017) (PubMed).
: "IDH-mutant glioma specific association of rs55705857 located at 8q24.21 involves MYC deregulation. ..." dans: Scientific reports, Vol. 6, pp. 27569, (2016) (PubMed).
: "Temozolomide promotes genomic and phenotypic changes in glioblastoma cells." dans: Cancer cell international, Vol. 16, pp. 36, (2016) (PubMed).
: "Impact of O6-methylguanine-DNA methyltransferase expression on the drug resistance of clear cell renal cell carcinoma." dans: Japanese journal of clinical oncology, (2015) (PubMed).
: "Quantitative Proteomics Analysis Reveals Novel Insights into Mechanisms of Action of Long Noncoding RNA Hox Transcript Antisense Intergenic RNA (HOTAIR) in HeLa Cells." dans: Molecular & cellular proteomics : MCP, Vol. 14, Issue 6, pp. 1447-63, (2015) (PubMed).
: "Proteomic Analysis of Cerebrospinal Fluid in Alzheimer's Disease: Wanted Dead or Alive." dans: Journal of Alzheimer's disease : JAD, (2014) (PubMed).
: "Profound prevention of experimental brain metastases of breast cancer by temozolomide in an MGMT-dependent manner." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 20, Issue 10, pp. 2727-39, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à MGMT
O-6-methylguanine-DNA methyltransferase (MGMT), O-6-methylguanine-DNA methyltransferase (Mgmt), Agat, AGT, AI267024Protein level used designations for MGMT
- 6-O-methylguanine-DNA methyltransferase
- O-6-methylguanine-DNA-alkyltransferase
- O6-methylguanine-DNA methyltransferase
- methylated-DNA--protein-cysteine methyltransferase
- methylguanine-DNA methyltransferase
- O-6-alkylguanine-DNA alkyltransferase
- 0-6-methylguanine-DNA methyltransferase
- O(6)-alkylguanine-DNA alkyltransferase
- O6-alkylguanine-DNA alkyltransferase
- O6-methylguanine-DNA methyltranferase
- O6-alkylguanine-DNA-alkyltransferase
- O6-methylguanine-DNA-methyltransferase
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