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MMP25 Produits

(Matrix Metallopeptidase 25 (MMP25))
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25. [provided by RefSeq, Jul 2008].

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Catégories MMP25 en vedette

MMP25 Anticorps

High quality antibodies with extensive validation data.

MMP25 Kits ELISA

Reliable ELISA kits for a wide range of species.

MMP25 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MMP25 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (6)
N° du produit ABIN7268422
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (5)
N° du produit ABIN7258762
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
N° du produit ABIN7242293
Quantité 200 μL
Fiche technique Fiche technique

MMP25 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6957696
Quantité 96 tests
Fiche technique Fiche technique

MMP25 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3083812
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3121955
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7395290
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits MMP25

Zhao, Sohail, Sun, Shi, Kim, Mobashery, Fridman: "Identification and role of the homodimerization interface of the glycosylphosphatidylinositol-anchored membrane type 6 matrix metalloproteinase (MMP25)." dans: The Journal of biological chemistry, Vol. 283, Issue 50, pp. 35023-32, (2008) (PubMed).

Sun, Weber, Sohail, Bernardo, Toth, Zhao, Turner, Fridman: "MMP25 (MT6-MMP) is highly expressed in human colon cancer, promotes tumor growth, and exhibits unique biochemical properties." dans: The Journal of biological chemistry, Vol. 282, Issue 30, pp. 21998-2010, (2007) (PubMed).

Matsuda, Itoh, Koshikawa, Akizawa, Yana, Seiki: "Clusterin, an abundant serum factor, is a possible negative regulator of MT6-MMP/MMP-25 produced by neutrophils." dans: The Journal of biological chemistry, Vol. 278, Issue 38, pp. 36350-7, (2003) (PubMed).

Velasco, Cal, Merlos-Suárez, Ferrando, Alvarez, Nakano, Arribas, López-Otín: "Human MT6-matrix metalloproteinase: identification, progelatinase A activation, and expression in brain tumors." dans: Cancer research, Vol. 60, Issue 4, pp. 877-82, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à MMP25

matrix metallopeptidase 25 (MMP25), matrix metallopeptidase 25 (Mmp25), F730048C11Rik, Leukolysin, MMP-25, MMP20, MMP20A, MMPL1, MT-MMP 6, MT-MMP6, MT6-MMP, MT6MMP, MTMMP6

Protein level used designations for MMP25

  • leukolysin
  • matrix metallopeptidase-like 1
  • matrix metalloproteinase 20
  • matrix metalloproteinase 25
  • matrix metalloproteinase-25
  • matrix metalloproteinase-like 1
  • membrane-type 6 matrix metalloproteinase
  • membrane-type matrix metalloproteinase 6
  • membrane-type-6 matrix metalloproteinase
  • MMP-25
  • LOW QUALITY PROTEIN: matrix metalloproteinase-25
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