MSH6 Produits
(MutS Homolog 6 (E. Coli) (MSH6))
Catégories
This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer. [provided by RefSeq, Jul 2008].
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Catégories MSH6 en vedette
MSH6 Anticorps
High quality antibodies with extensive validation data.
MSH6 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
MSH6 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, ELISA, ICC, FACS
Validations
- (1)
- (7)
N° du produit
ABIN969293
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, ELISA, ICC, FACS
Validations
- (8)
N° du produit
ABIN7193706
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, ELISA, IF, Coat, FACS, StM
Validations
- (7)
N° du produit
ABIN6939580
Quantité
100 μg
Fiche technique
Fiche technique
MSH6 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1311444
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3093948
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3134489
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits MSH6
: "Successful immune checkpoint blockade in a patient with advanced stage microsatellite-unstable biliary tract cancer." dans: Cold Spring Harbor molecular case studies, Vol. 3, Issue 5, (2017) (PubMed).: "DNA mismatch repair proteins are required for efficient herpes simplex virus 1 replication." dans: Journal of virology, Vol. 85, Issue 23, pp. 12241-53, (2011) (PubMed).
: "Mismatch-repair protein MSH6 is associated with Ku70 and regulates DNA double-strand break repair." dans: Nucleic acids research, Vol. 39, Issue 6, pp. 2130-43, (2011) (PubMed).
: "Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90." dans: The Journal of experimental medicine, Vol. 207, Issue 12, pp. 2751-65, (2010) (PubMed).
: "Modulation of mismatch repair and genomic stability by miR-155. ..." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 15, pp. 6982-7, (2010) (PubMed).
: "Estrogen receptor alpha gene polymorphism and endometrial cancer risk--a case-control study." dans: BMC cancer, Vol. 8, pp. 322, (2009) (PubMed).
: "Rab39a binds caspase-1 and is required for caspase-1-dependent interleukin-1beta secretion." dans: The Journal of biological chemistry, Vol. 284, Issue 50, pp. 34531-7, (2009) (PubMed).
: "Germ-line mutations in mismatch repair genes associated with prostate cancer." dans: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 9, pp. 2460-7, (2009) (PubMed).
: "Mismatch Repair proteins are recruited to replicating DNA through interaction with Proliferating Cell Nuclear Antigen (PCNA)." dans: Nucleic acids research, Vol. 36, Issue 1, pp. 67-75, (2008) (PubMed).
: "Hereditary cancer-associated missense mutations in hMSH6 uncouple ATP hydrolysis from DNA mismatch binding." dans: The Journal of biological chemistry, Vol. 283, Issue 46, pp. 31641-8, (2008) (PubMed).
Synonymes et noms alternatifs relatifs à MSH6
mutS homolog 6 (MSH6), mutS homolog 6 (E. coli) (msh6), mutS homolog 6 (msh6), mutS homolog 6 (Msh6), DNA mismatch repair protein (msh6), AU044881, AW550279, cb326, GTBP, GTMBP, Gtmbp, HNPCC5, HSAP, LOC100227810, p160, wu:fb36c12Protein level used designations for MSH6
- DNA mismatch repair protein Msh6
- G/T mismatch-binding protein
- mutS-alpha 160 kDa subunit
- sperm-associated protein
- mutS homolog 6 (E. coli)
- DNA mismatch repair protein Msh6-like
- g/T mismatch-binding protein
- p160
- rCG61559-like
- LOW QUALITY PROTEIN: DNA mismatch repair protein Msh6
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