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MTHFR Produits

(Methylenetetrahydrofolate Reductase (NAD(P)H) (MTHFR))

Catégories

The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009].

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Catégories MTHFR en vedette

MTHFR Anticorps

High quality antibodies with extensive validation data.

MTHFR Kits ELISA

Reliable ELISA kits for a wide range of species.

MTHFR Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MTHFR recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Rat
Application IHC, ELISA, WB
Validations
  • (2)
  • (5)
N° du produit ABIN969297
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Rat
Application EIA, IHC (p), WB
Validations
  • (5)
N° du produit ABIN1108309
Quantité 0.1 mL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB
Validations
  • (2)
N° du produit ABIN2854784
Quantité 100 μL
Fiche technique Fiche technique

MTHFR recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6957798
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6230640
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Cow
Analytical Method
Validations
N° du produit ABIN1142379
Quantité 96 tests
Fiche technique Fiche technique

MTHFR recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3084059
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3120041
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN2726510
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits MTHFR

Khot, Yadav, Shrestha, Kaur, Sundrani, Chavan-Gautam, Mehendale, Chandak, Joshi: "Hypermethylated CpG sites in the MTR gene promoter in preterm placenta." dans: Epigenomics, Vol. 9, Issue 7, pp. 985-996, (2018) (PubMed).

Genovese, Gualandi, Taddia, Marverti, Pirondi, Marraccini, Perco, Pelà, Guerrini, Amoroso, Esposito, Martello, Ponterini, DArca, Costi: "Mass spectrometric/bioinformatic identification of a protein subset that characterizes the cellular activity of anticancer peptides." dans: Journal of proteome research, Vol. 13, Issue 11, pp. 5250-61, (2014) (PubMed).

Forges, Chery, Audonnet, Feillet, Gueant: "Life-threatening methylenetetrahydrofolate reductase (MTHFR) deficiency with extremely early onset: characterization of two novel mutations in compound heterozygous patients." dans: Molecular genetics and metabolism, Vol. 100, Issue 2, pp. 143-8, (2010) (PubMed).

Sonne: "WITHDRAWN: Health effects from long-range transported contaminants in Arctic top predators: An integrated review based on studies of polar bears and relevant model species." dans: Environment international, (2010) (PubMed).

Singh, Singh, Raman: "MTHFR A1298C polymorphism and idiopathic male infertility." dans: Journal of postgraduate medicine, Vol. 56, Issue 4, pp. 267-9, (2010) (PubMed).

Harisha, Devi, Christopher, Kruthika-Vinod: "Impact of 5,10-methylenetetrahydrofolate reductase gene polymorphism on neural tube defects." dans: Journal of neurosurgery. Pediatrics, Vol. 6, Issue 4, pp. 364-7, (2010) (PubMed).

Wu, Chang, Tsai, Lin, Wang, Tsai, Chen, Yao, Chiu, Bau, Lin: "Significant association of methylenetetrahydrofolate reductase single nucleotide polymorphisms with prostate cancer susceptibility in taiwan." dans: Anticancer research, Vol. 30, Issue 9, pp. 3573-7, (2010) (PubMed).

Magnowski, Seremak-Mrozikiewicz, Nowak-Markwitz, Kurzawińska, Drews, Spaczyński: "[No association between MTHFR 677C>T polymorphism and ovarian cancer risk in BRCA1 mutation carriers in Wielkopolska region]." dans: Ginekologia polska, Vol. 81, Issue 7, pp. 506-10, (2010) (PubMed).

Kristensen, Pedersen, Melsen, Ellehauge, Mejer: "Variants in the dihydropyrimidine dehydrogenase, methylenetetrahydrofolate reductase and thymidylate synthase genes predict early toxicity of 5-fluorouracil in colorectal cancer patients." dans: The Journal of international medical research, Vol. 38, Issue 3, pp. 870-83, (2010) (PubMed).

Sarecka-Hujar, Zak, Krauze: "Carrier-state of two or three polymorphic variants of MTHFR, IL-6 and ICAM1 genes increases the risk of coronary artery disease." dans: Kardiologia polska, Vol. 66, Issue 12, pp. 1269-77, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à MTHFR

methylenetetrahydrofolate reductase (NAD(P)H) L homeolog (mthfr.L), methylenetetrahydrofolate reductase (MTHFR), methylenetetrahydrofolate reductase (NAD(P)H) (mthfr), methylenetetrahydrofolate reductase (metF), methylenetetrahydrofolate reductase (DDB_G0279137), 5,10-methylenetetrahydrofolate reductase (Mthfr), methylenetetrahydrofolate reductase (Mthfr), AI323986, DDBDRAFT_0204686, DDBDRAFT_0230137, DDB_0204686, DDB_0230137

Protein level used designations for MTHFR

  • 5,10-methylenetetrahydrofolate reductase
  • 5,10-methylenetetrahydrofolate reductase (NADPH)
  • methylenetetrahydrofolate reductase (NAD(P)H)
  • methylenetetrahydrofolate reductase-like
  • methylenetetrahydrofolate reductase
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