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NCOA3 Produits

(Nuclear Receptor Coactivator 3 (NCOA3))
The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein. [provided by RefSeq, Mar 2010].

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Catégories NCOA3 en vedette

NCOA3 Anticorps

High quality antibodies with extensive validation data.

NCOA3 Kits ELISA

Reliable ELISA kits for a wide range of species.

NCOA3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

NCOA3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p), IHC (fro), ICC
Validations
  • (5)
N° du produit ABIN7441217
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (4)
N° du produit ABIN7074886
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p)
Validations
  • (3)
N° du produit ABIN3187987
Quantité 100 μL
Fiche technique Fiche technique

NCOA3 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6958248
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958249
Quantité 96 tests
Fiche technique Fiche technique

NCOA3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1312128
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3131361
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3094095
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits NCOA3

Zhou, Wei, Chen, Dong, Lai, Fang, Jiang, Lu, Zhou, Xie, Luo, Chen: "Identification and validation of AIB1 and EIF5A2 for noninvasive detection of bladder cancer in urine samples." dans: Oncotarget, Vol. 7, Issue 27, pp. 41703-41714, (2016) (PubMed).

Battistella, Romero, Castro-Vega, Gapihan, Bouhidel, Bagot, Feugeas, Janin: "The High Expression of the microRNA 17-92 Cluster and its Paralogs, and the Downregulation of the Target Gene PTEN, Is Associated with Primary Cutaneous B-Cell Lymphoma Progression." dans: The Journal of investigative dermatology, Vol. 135, Issue 6, pp. 1659-67, (2015) (PubMed).

Pu, Ye, Spitz, Wang, Gu, Lippman, Hildebrandt, Hong, Minna, Roth, Yang, Wu: "Predictors of survival in never-smokers with non-small cell lung cancer: a large-scale, two-phase genetic study." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 18, Issue 21, pp. 5983-91, (2012) (PubMed).

Cai, Shames, Raso, Xie, Kim, Pollack, Girard, Sullivan, Gao, Peyton, Nanjundan, Byers, Heymach, Mills, Gazdar, Wistuba, Kodadek, Minna: "Steroid receptor coactivator-3 expression in lung cancer and its role in the regulation of cancer cell survival and proliferation." dans: Cancer research, Vol. 70, Issue 16, pp. 6477-85, (2010) (PubMed).

Kovanen, Saarikoski, Haukka, Pirkola, Aromaa, Lönnqvist, Partonen: "Circadian clock gene polymorphisms in alcohol use disorders and alcohol consumption." dans: Alcohol and alcoholism (Oxford, Oxfordshire), Vol. 45, Issue 4, pp. 303-11, (2010) (PubMed).

Karmakar, Gao, Pace, Oesterreich, Smith: "Cooperative activation of cyclin D1 and progesterone receptor gene expression by the SRC-3 coactivator and SMRT corepressor." dans: Molecular endocrinology (Baltimore, Md.), Vol. 24, Issue 6, pp. 1187-202, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." dans: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

Lanz, Bulynko, Malovannaya, Labhart, Wang, Li, Qin, Harper, OMalley: "Global characterization of transcriptional impact of the SRC-3 coregulator." dans: Molecular endocrinology (Baltimore, Md.), Vol. 24, Issue 4, pp. 859-72, (2010) (PubMed).

Heemers, Regan, Schmidt, Anderson, Ballman, Tindall: "Androgen modulation of coregulator expression in prostate cancer cells." dans: Molecular endocrinology (Baltimore, Md.), Vol. 23, Issue 4, pp. 572-83, (2009) (PubMed).

Harigopal, Heymann, Ghosh, Anagnostou, Camp, Rimm: "Estrogen receptor co-activator (AIB1) protein expression by automated quantitative analysis (AQUA) in a breast cancer tissue microarray and association with patient outcome." dans: Breast cancer research and treatment, Vol. 115, Issue 1, pp. 77-85, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à NCOA3

nuclear receptor coactivator 3 (NCOA3), nuclear receptor coactivator 3 (Ncoa3), nuclear receptor coactivator 3 S homeolog (ncoa3.S), 2010305B15Rik, ACTR, Actr, actr, AIB-1, aib-1, AIB1, Aib1, aib1, AW321064, bHLHe42, CAGH16, cagh16, CTG26, ctg26, KAT13B, kat13b, NCOA3, p/Cip, pCIP, pCip, pcip, RAC3, Rac3, rac3, SRC-3, src-3, SRC3, Src3, src3, TNRC14, tnrc14, TNRC16, tnrc16, TRAM-1, Tram-1, tram-1, Tram1, xSRC-3

Protein level used designations for NCOA3

  • nuclear receptor coactivator 3
  • CBP-interacting protein
  • amplified in breast cancer 1 protein
  • class E basic helix-loop-helix protein 42
  • receptor-associated coactivator 3
  • steroid receptor coactivator protein 3
  • thyroid hormone receptor activator molecule 1
  • steroid receptor coactivator 3
  • AIB-1
  • NCoA-3
  • RAC-3
  • SRC-3
  • amplified in breast cancer-1 protein homolog
  • retinoid X receptor-interacting coactivator xSRC-3
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