NCOR2 Produits
(Nuclear Receptor Co-Repressor 2 (NCOR2))
Catégories
This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011].
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Catégories NCOR2 en vedette
NCOR2 Anticorps
High quality antibodies with extensive validation data.
NCOR2 Kits ELISA
Reliable ELISA kits for a wide range of species.
NCOR2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (4)
N° du produit
ABIN6144422
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
- (2)
N° du produit
ABIN686302
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (1)
N° du produit
ABIN564153
Quantité
50 μL
Fiche technique
Fiche technique
NCOR2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969004
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969005
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative DNA-Binding ELISA
Validations
N° du produit
ABIN5648559
Quantité
96 tests
Fiche technique
Fiche technique
NCOR2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1312140
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits NCOR2
: "SpliceArray profiling of breast cancer reveals a novel variant of NCOR2/SMRT that is associated with tamoxifen resistance and control of ER? transcriptional activity." dans: Cancer research, Vol. 73, Issue 1, pp. 246-55, (2013) (PubMed).: "miR-16 targets transcriptional corepressor SMRT and modulates NF-kappaB-regulated transactivation of interleukin-8 gene." dans: PLoS ONE, Vol. 7, Issue 1, pp. e30772, (2012) (PubMed).
: "In vivo and in vitro evidence that PPARγ ligands are antagonists of leptin signaling in breast cancer." dans: The American journal of pathology, Vol. 179, Issue 2, pp. 1030-40, (2011) (PubMed).
: "Regulation of androgen receptor activity by the nuclear receptor corepressor SMRT." dans: The Journal of biological chemistry, Vol. 278, Issue 7, pp. 5052-61, (2003) (PubMed).
: "Repressors of androgen and progesterone receptor action." dans: The Journal of biological chemistry, Vol. 278, Issue 33, pp. 31136-48, (2003) (PubMed).
: "SMRTE inhibits MEF2C transcriptional activation by targeting HDAC4 and 5 to nuclear domains." dans: The Journal of biological chemistry, Vol. 276, Issue 26, pp. 24177-85, (2001) (PubMed).
: "Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway." dans: Genes & development, Vol. 14, Issue 1, pp. 45-54, (2000) (PubMed).
: "Unique forms of human and mouse nuclear receptor corepressor SMRT." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 6, pp. 2639-44, (1999) (PubMed).
: "The nuclear corepressors NCoR and SMRT are key regulators of both ligand- and 8-bromo-cyclic AMP-dependent transcriptional activity of the human progesterone receptor." dans: Molecular and cellular biology, Vol. 18, Issue 3, pp. 1369-78, (1998) (PubMed).
: "Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase." dans: Cell, Vol. 89, Issue 3, pp. 373-80, (1997) (PubMed).
Synonymes et noms alternatifs relatifs à NCOR2
nuclear receptor corepressor 2 (NCOR2), nuclear receptor co-repressor 2 (Ncor2), nuclear receptor corepressor 2 (ncor2), nuclear receptor co-repressor 2 (NCOR2), CTG26, ctg26, gb:be017685, N-CoR, N-CoR2, NCOR2, si:bz71m17.2, SMAP270, SMRT, smrt, SMRTE, SMRTe, smrte, SMRTE-tau, smrte-tau, TNRC14, tnrc14, TRAC, TRAC-1, trac-1, TRAC1, trac1Protein level used designations for NCOR2
- CTG repeat protein 26
- T3 receptor-associating factor
- silencing mediator for retinoid and thyroid hormone receptors
- thyroid-, retinoic-acid-receptor-associated corepressor
- nuclear receptor corepressor 2
- nuclear receptor co-repressor 2
- N-CoR2
- TRAC
- silencing mediator of retinoic acid and thyroid hormone receptor
- silencing mediator of retinoid acid and thyroid hormone receptor
- silencing mediator
- thyroid hormone receptor
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