NEU1 Produits
(Sialidase 1 (Lysosomal Sialidase) (NEU1))
Catégories
The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity. [provided by RefSeq, Jul 2008].
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Catégories NEU1 en vedette
NEU1 Anticorps
High quality antibodies with extensive validation data.
NEU1 Kits ELISA
Reliable ELISA kits for a wide range of species.
NEU1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
NEU1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (9)
N° du produit
ABIN7438058
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (9)
N° du produit
ABIN1491548
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (5)
N° du produit
ABIN1774878
Quantité
100 μg
Fiche technique
Fiche technique
NEU1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6973751
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN5518637
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN511750
Quantité
96 tests
Fiche technique
Fiche technique
NEU1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7125087
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1312399
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3084304
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits NEU1
: "Assessment of total sialic acid levels in patients with hyperemesis gravidarum: a preliminary study." dans: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, Vol. 38, Issue 4, pp. 532-535, (2018) (PubMed).: "Elevated expression of NEU1 sialidase in idiopathic pulmonary fibrosis provokes pulmonary collagen deposition, lymphocytosis, and fibrosis." dans: American journal of physiology. Lung cellular and molecular physiology, Vol. 310, Issue 10, pp. L940-54, (2017) (PubMed).
: "The NEU1-selective sialidase inhibitor, C9-butyl-amide-DANA, blocks sialidase activity and NEU1-mediated bioactivities in human lung in vitro and murine lung in vivo." dans: Glycobiology, Vol. 26, Issue 8, pp. 834-49, (2016) (PubMed).
: "CodY is a global regulator of virulence-associated properties for Clostridium perfringens type D strain CN3718." dans: mBio, Vol. 4, Issue 5, pp. e00770-13, (2013) (PubMed).
: "Type II sialidosis: review of the clinical spectrum and identification of a new splicing defect with chitotriosidase assessment in two patients." dans: Journal of neurology, Vol. 256, Issue 11, pp. 1911-5, (2009) (PubMed).
: "A longitudinal study of Taiwanese sialidosis type 1: an insight into the concept of cherry-red spot myoclonus syndrome." dans: European journal of neurology : the official journal of the European Federation of Neurological Societies, Vol. 16, Issue 8, pp. 912-9, (2009) (PubMed).
: "Heterodimerization of the sialidase NEU1 with the chaperone protective protein/cathepsin A prevents its premature oligomerization." dans: The Journal of biological chemistry, Vol. 284, Issue 41, pp. 28430-41, (2009) (PubMed).
Synonymes et noms alternatifs relatifs à NEU1
neuraminidase 1 (NEU1), neuraminidase 1 (lysosomal sialidase) L homeolog (neu1.L), neuraminidase 1 (neu1), neuraminidase 1 (Neu1), AA407268, AA407316, Aglp, Apl, Bat-7, Bat7, G9, Map-2, MGC81958, NANH, NEU, Neu, Neu-1, SIAL1Protein level used designations for NEU1
- G9 sialidase
- N-acetyl-alpha-neuraminidase 1
- acetylneuraminyl hydrolase
- exo-alpha-sialidase
- lysosomal sialidase
- sialidase-1
- sialidase 1 (lysosomal sialidase)
- neuraminidase
- isotocin
- Isotocin-neurophysin IT 1
- neuraminidase 1
- sialidase-1-like
- HLA-B-associated transcript 7
- sialidase 1
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