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Neuregulin 2 Produits

(Neuregulin 2 (NRG2))
This gene encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcript variants encoding distinct isoforms have been described. [provided by RefSeq, May 2010].

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Catégories Neuregulin 2 en vedette

Neuregulin 2 Anticorps

High quality antibodies with extensive validation data.

Neuregulin 2 Kits ELISA

Reliable ELISA kits for a wide range of species.

Neuregulin 2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Neuregulin 2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse, Rat
Application WB, IHC, IF
Validations
  • (4)
N° du produit ABIN7074804
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (3)
N° du produit ABIN564118
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
N° du produit ABIN7164305
Quantité 100 μg
Fiche technique Fiche technique

Neuregulin 2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958087
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958088
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Competition ELISA
Validations
N° du produit ABIN2112779
Quantité 96 tests
Fiche technique Fiche technique

Neuregulin 2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1313024
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3084550
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3084549
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits Neuregulin 2

Frogne, Benjaminsen, Sonne-Hansen, Sorensen, Nexo, Laenkholm, Rasmussen, Riese, de Cremoux, Stenvang, Lykkesfeldt: "Activation of ErbB3, EGFR and Erk is essential for growth of human breast cancer cell lines with acquired resistance to fulvestrant." dans: Breast cancer research and treatment, Vol. 114, Issue 2, pp. 263-75, (2009) (PubMed).

Yamada, Ichino, Nishii, Sawada, Higashiyama, Ishiguro, Nagatsu: "Characterization of the human NTAK gene structure and distribution of the isoforms for rat NTAK mRNA." dans: Gene, Vol. 255, Issue 1, pp. 15-24, (2000) (PubMed).

Ring, Chang, Guilbot, Brice, LeGuern, Francke: "The human neuregulin-2 (NRG2) gene: cloning, mapping and evaluation as a candidate for the autosomal recessive form of Charcot-Marie-Tooth disease linked to 5q." dans: Human genetics, Vol. 104, Issue 4, pp. 326-32, (1999) (PubMed).

Higashiyama, Horikawa, Yamada, Ichino, Nakano, Nakagawa, Miyagawa, Matsushita, Nagatsu, Taniguchi, Ishiguro: "A novel brain-derived member of the epidermal growth factor family that interacts with ErbB3 and ErbB4." dans: Journal of biochemistry, Vol. 122, Issue 3, pp. 675-80, (1998) (PubMed).

Carraway, Weber, Unger, Ledesma, Yu, Gassmann, Lai: "Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases." dans: Nature, Vol. 387, Issue 6632, pp. 512-6, (1997) (PubMed).

Busfield, Michnick, Chickering, Revett, Ma, Woolf, Comrack, Dussault, Woolf, Goodearl, Gearing: "Characterization of a neuregulin-related gene, Don-1, that is highly expressed in restricted regions of the cerebellum and hippocampus." dans: Molecular and cellular biology, Vol. 17, Issue 7, pp. 4007-14, (1997) (PubMed).

Synonymes et noms alternatifs relatifs à Neuregulin 2

neuregulin 2 (NRG2), neuregulin 2 (Nrg2), Don1, DON1, HRG2, NRG2, NTAK, Ntak, NTAK_alpha2a

Protein level used designations for Neuregulin 2

  • neuregulin 2
  • pro-NRG2
  • pro-neuregulin-2, membrane-bound isoform
  • divergent of neuregulin-1
  • neural- and thymus-derived activator for ErbB kinases
  • NTAK alpha1
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