The neuregulins, including NRG4, activate type-1 growth factor receptors (see EGFR\; MIM 131550) to initiating cell-to-cell signaling through tyrosine phosphorylation (Harari et al., 1999 [PubMed 10348342]).[supplied by OMIM, Mar 2008].
custom-made
NRG4
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
NRG4
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
NRG4
Origine: Souris
Hôte: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
custom-made
NRG4
Origine: Humain
Hôte: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
Dernières publications pour nos Neuregulin 4 Protéines
McElroy, Castle, Bernard, Almohazey, Hunter, Bell, Al Alam, Wang, Ford, Frey: "The ErbB4 ligand neuregulin-4 protects against experimental necrotizing enterocolitis." dans: The American journal of pathology, Vol. 184, Issue 10, pp. 2768-78, (2016) (PubMed).
Ng, Lee, Supko, Khan, Torres, Berwick, Ho, Kirkwood, Siegfried, Stabile: "Pan-erbB inhibition potentiates BRAF inhibitors for melanoma treatment." dans: Melanoma research, Vol. 24, Issue 3, pp. 207-18, (2014) (PubMed).
Liu, Tefft, Roberts, Zhang, Ren, Li, Huang, Zhang, Phillips, Wu: "Cardioprotective proteins upregulated in the liver in response to experimental myocardial ischemia." dans: American journal of physiology. Heart and circulatory physiology, Vol. 303, Issue 12, pp. H1446-58, (2012) (PubMed).
Hayes, Blackburn, Boyle, Russell, Frost, Morgan, Gullick: "Expression of neuregulin 4 splice variants in normal human tissues and prostate cancer and their effects on cell motility." dans: Endocrine-related cancer, Vol. 18, Issue 1, pp. 39-49, (2010) (PubMed).