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NGEF Protéines

(Neuronal Guanine Nucleotide Exchange Factor (NGEF))

Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity).

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NGEF Protein (AA 1-710) (His tag)

custom-made NGEF Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Ngef Protein, UniprotID Q8CHT1

3 images

N° du produit ABIN7564588

Détails

NGEF Protein (AA 1-710) (His tag)

custom-made NGEF Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant NGEF Protein, UniprotID Q8N5V2

3 images

N° du produit ABIN7554726

Détails

NGEF Protein (AA 612-710) (GST tag)

NGEF Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AP, AA

Image no. 1 for Neuronal Guanine Nucleotide Exchange Factor (NGEF) (AA 612-710) protein (GST tag) (ABIN1312527)

1 image

N° du produit ABIN1312527

Détails

NGEF Protein (AA 1-710) (Strep Tag)

custom-made NGEF Origine: Souris Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

N° du produit ABIN3136476

Détails

NGEF Protein (AA 1-710) (Strep Tag)

custom-made NGEF Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

N° du produit ABIN3094103